Answered: 13. Flumazenil is the antidote for… | bartleby

Essentials of Pharmacology for Health Professions

Essentials of Pharmacology for Health Professions

7th Edition

ISBN:9781305441620

Author:WOODROW

Publisher:WOODROW

Chapter16: Gastrointestinal Drugs

Section: Chapter Questions

Problem 16CRQ

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Question

13. Flumazenil is the antidote for benzodiazepine overdose, acting as a competitive antagonist at GABAa
receptors in the CNS. The effective dose of flumazenil to treat overdose thus depends on which of the
following benzodiazepine properties?
a) Intrinsic activity and dose
b) Receptor affinity and dose
c) Selectivity and intrinsic activity
d) Selectivity and receptor affinity
e) Selectivity and dose

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