10. The genes Stubble (Sb), Lyra (Ly), and bright (br) are all linked on chromosome 3 in Drosophila fruit flies. An organism that was heterozygous for all three genes was mated to an organism that was homozygous recessive for all three. The following phenotypes were seen in the offspring: All wild-type 422 Lyra and Stubble 4 Stubble and bright 16 Lyra and bright 75 Lyra only 18 Stubble only 59 Bright only 2 Lyra, Stubble, and bright 404 f. What are the alleles in the parental gametes? g. What are the alleles in the double crossover gametes? h. What gene is in the middle of the three? i. Draw a genetic map of the Stubble, Lyra, and bright genes and label the map distance between them.

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The text presents a genetic problem involving linked genes in Drosophila fruit flies. Here's a transcription suitable for an educational website:

---

**Genetic Linkage in Drosophila: A Problem Set**

*Problem 10:*

The genes *Stubble (Sb)*, *Lyra (Ly)*, and *bright (br)* are all linked on chromosome 3 in *Drosophila* fruit flies. An organism that was heterozygous for all three genes was mated to an organism that was homozygous recessive for all three. The following phenotypes were observed in the offspring:

- **All wild-type:** 422
- **Lyra and Stubble:** 4
- **Stubble and bright:** 16
- **Lyra and bright:** 75
- **Lyra only:** 18
- **Stubble only:** 59
- **Bright only:** 2
- **Lyra, Stubble, and bright:** 404

**Questions:**

f. What are the alleles in the parental gametes?

g. What are the alleles in the double crossover gametes?

h. What gene is in the middle of the three?

i. Draw a genetic map of the *Stubble*, *Lyra*, and *bright* genes and label the map distances between them.

---

For the explanation of parts (f) to (i), the students are expected to use genetic principles to deduce linkage and recombination information, potentially drawing on previously learned knowledge about genetic mapping and linkage analysis. 

(Note: Since there are no graphical elements or diagrams present, there's no need for further explanation on this aspect.)
Transcribed Image Text:The text presents a genetic problem involving linked genes in Drosophila fruit flies. Here's a transcription suitable for an educational website: --- **Genetic Linkage in Drosophila: A Problem Set** *Problem 10:* The genes *Stubble (Sb)*, *Lyra (Ly)*, and *bright (br)* are all linked on chromosome 3 in *Drosophila* fruit flies. An organism that was heterozygous for all three genes was mated to an organism that was homozygous recessive for all three. The following phenotypes were observed in the offspring: - **All wild-type:** 422 - **Lyra and Stubble:** 4 - **Stubble and bright:** 16 - **Lyra and bright:** 75 - **Lyra only:** 18 - **Stubble only:** 59 - **Bright only:** 2 - **Lyra, Stubble, and bright:** 404 **Questions:** f. What are the alleles in the parental gametes? g. What are the alleles in the double crossover gametes? h. What gene is in the middle of the three? i. Draw a genetic map of the *Stubble*, *Lyra*, and *bright* genes and label the map distances between them. --- For the explanation of parts (f) to (i), the students are expected to use genetic principles to deduce linkage and recombination information, potentially drawing on previously learned knowledge about genetic mapping and linkage analysis. (Note: Since there are no graphical elements or diagrams present, there's no need for further explanation on this aspect.)
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