I. In the fruit fly Drosophila melanogaster, tan body color (B) is dominant to black (b), and dark red eyes (E) is dominant to bright orange (e). A black fly, heterozygous for eye color (Fly #1) is crossed to an orange eyed fly, heterozygous for body color (Fly #2). What are... Genotypes of the parents? Gametes from each parent? Ratios of gametes from each parent? Complete the following Punnett square. Indicate gamete genotypes from each parent and all offspring genotypes. Fly #1 What proportion of offspring are... Tan & dark red? Tan & orange? Black & dark red? Black & orange? #1 #1 #1 Fly #2 x #2 #2 #2

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### BIO 340 Activity #3: Hybrid Crosses, Probability & Pedigrees

**Name (Last, First):** _____________________

---

#### I. Genetics of Drosophila Melanogaster

In the fruit fly *Drosophila melanogaster*, tan body color (B) is dominant to black (b), and dark red eyes (E) is dominant to bright orange (e). A black fly, heterozygous for eye color (Fly #1) is crossed to an orange-eyed fly, heterozygous for body color (Fly #2).

1. **Genotypes of the parents?**
   - Fly #1: _______________ 
   - Fly #2: _______________

2. **Gametes from each parent?**
   - Fly #1: _______________
   - Fly #2: _______________

3. **Ratios of gametes from each parent?**
   - Fly #1: _______________
   - Fly #2: _______________

**Complete the following Punnett square.** Indicate gamete genotypes from each parent and all offspring genotypes.

- What proportion of offspring are:
  - Tan & dark red: __________
  - Tan & orange: __________
  - Black & dark red: __________
  - Black & orange: __________

Diagram: A blank 4x4 Punnett square is shown, labeled for Fly #1 and Fly #2 gametes.

---

#### II. Probability Calculations

What is the probability that this pair of parents will produce the indicated offspring?

- **Genotypes: Aa Bb DD x aa Bb Dd ➔ Aa Bb Dd**

**Punnett squares for each trait can help with this calculation!**

- Probability (P) of Aa Bb Dd = P (Aa) ____ x P (Bb) ____ x P (Dd) ____ = ____

Diagram: Three blank Punnett squares corresponding to each genetic trait.

---

#### III. Analysis of Pedigrees

For each of these three pedigrees, determine the likely mode of inheritance and the probability that the individual marked with a diamond (◇) will express the trait.

**A. Pedigree with Generations I-IV**

1. **Mode of Inheritance:** _____________________
2. **Probability that ◇ expresses the trait:** ______

**B. Pedigree with Generations I-IV**

(C1) Mode of Inheritance: __________________
Transcribed Image Text:### BIO 340 Activity #3: Hybrid Crosses, Probability & Pedigrees **Name (Last, First):** _____________________ --- #### I. Genetics of Drosophila Melanogaster In the fruit fly *Drosophila melanogaster*, tan body color (B) is dominant to black (b), and dark red eyes (E) is dominant to bright orange (e). A black fly, heterozygous for eye color (Fly #1) is crossed to an orange-eyed fly, heterozygous for body color (Fly #2). 1. **Genotypes of the parents?** - Fly #1: _______________ - Fly #2: _______________ 2. **Gametes from each parent?** - Fly #1: _______________ - Fly #2: _______________ 3. **Ratios of gametes from each parent?** - Fly #1: _______________ - Fly #2: _______________ **Complete the following Punnett square.** Indicate gamete genotypes from each parent and all offspring genotypes. - What proportion of offspring are: - Tan & dark red: __________ - Tan & orange: __________ - Black & dark red: __________ - Black & orange: __________ Diagram: A blank 4x4 Punnett square is shown, labeled for Fly #1 and Fly #2 gametes. --- #### II. Probability Calculations What is the probability that this pair of parents will produce the indicated offspring? - **Genotypes: Aa Bb DD x aa Bb Dd ➔ Aa Bb Dd** **Punnett squares for each trait can help with this calculation!** - Probability (P) of Aa Bb Dd = P (Aa) ____ x P (Bb) ____ x P (Dd) ____ = ____ Diagram: Three blank Punnett squares corresponding to each genetic trait. --- #### III. Analysis of Pedigrees For each of these three pedigrees, determine the likely mode of inheritance and the probability that the individual marked with a diamond (◇) will express the trait. **A. Pedigree with Generations I-IV** 1. **Mode of Inheritance:** _____________________ 2. **Probability that ◇ expresses the trait:** ______ **B. Pedigree with Generations I-IV** (C1) Mode of Inheritance: __________________
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