+1 - Human - Fly - Yeast - 1000 -500 500 1000 Nucleosome distance from TSS (bp) A FIGURE 26.16 Distribution of H2A.Z-containing nucleosomes near a transcription start site (TSS). In human, Drosophila, and yeast cells, H2A.Z is most abundant in nucleosomes at positions +1 and –1 relative to the TSS. These data were obtained by chromatin immunoprecipitation (see Tools of Biochemistry 24B). H2A.Z Nucleosome level
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
Refer to figure, which shows the distribution of histone H2A.Z on nucleosomes near a transcription start site. What experimental technique would have been used to generate the data for this figure? Briefly describe the operation of this technique.
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