Experiment #1

Answer the following questions following a Solubility and recrystalization lab for organic chemisty.  1. In a solubility and recrystallization lab you are working with the following chemicals : solids (benzoic acid, acetanilide,naphthalene, and resorcinol) and three solvents (water, ethanol and petroleumether) discuss and rank the polarity of the solvents and the polarity of the compounds being investigated. 2. Briefly describe how a mixture of sand and benzoic acid (soluble in hotwater) could be separated to produce pure benzoic acid.

Data: Density of p-phenetidine is 1.065g/mol Williamson Ether Synthesis: Mass of filter paper:   0.680 g Mass of filter paper and product:  1.482 g Melting Point:  134-136oC Amide Synthesis: Mass of filter paper:   0.686 g Mass of filter paper and product: 1.589 g Melting Point:  135-137oC Mixed Melting Point (product of amide synthesis mixed with Williamson Ether synthesis product): 134-136oC (a)Calculate theoretical yield of both williamson ether synthesis of phenacetine and amide synthesis of phenacetin. (b) calculate the percent yield of phenacetin obtained via williamson ether synthesis. (c) Calculate the percent yeild of phenacetin obtained via the amide synthesis.

Please answer the question at the bottom, Thanks. LAB NOTES FOR PREPARATION OF BUTYL MAGNESIUM BROMIDEAND ITS SUBSEQUENT CONVERSION TO AN ALCOHOL To the reaction flask were added 2.5967 gram of magnesium turnings, about 20 mlof diglyme, and a solution of 13.5942 gram of butyl bromide in about 25 mldiglyme.The procedure as per the lab manual was initiated. After the required heating timewas completed the reaction mixture was allowed to cool to room temperature.Then a solution of 6.1123 gram of acetone in about 15 ml of diglyme was addeddropwise as per the lab manual.The rest of the lab manual procedure was completed, ultimately affording 2.5532gram of an oily, clear and slightly yellow liquid, presumed to be 2-methyl-2-hexanol. Boiling point as measured by distillation was 138 – 141 deg C.About 0.8 ml of the presumed 2-methyl-2-hexanol was placed in an NMR tube towhich was added 2 drops of TMS. The tube was capped, then inverted and righted20 times to thoroughly mix the product and…

Please answer the question at the bottom, Thanks. LAB NOTES FOR PREPARATION OF BUTYL MAGNESIUM BROMIDEAND ITS SUBSEQUENT CONVERSION TO AN ALCOHOL To the reaction flask were added 2.5967 gram of magnesium turnings, about 20 mlof diglyme, and a solution of 13.5942 gram of butyl bromide in about 25 mldiglyme.The procedure as per the lab manual was initiated. After the required heating timewas completed the reaction mixture was allowed to cool to room temperature.Then a solution of 6.1123 gram of acetone in about 15 ml of diglyme was addeddropwise as per the lab manual.The rest of the lab manual procedure was completed, ultimately affording 2.5532gram of an oily, clear and slightly yellow liquid, presumed to be 2-methyl-2-hexanol. Boiling point as measured by distillation was 138 – 141 deg C.About 0.8 ml of the presumed 2-methyl-2-hexanol was placed in an NMR tube towhich was added 2 drops of TMS. The tube was capped, then inverted and righted20 times to thoroughly mix the product and…

Starting Materials CH3B CH3CH2BR CH3CH2CH,Br C6H5Br Reagents Mg, ether 1. a. 2. 13CH2-13C-OH b. 13CO2 then H3O* 3. LIAIH4 then H3o* PBr3 CO2 then H30* C. 4. d. 5. C6HsCH2Br е. Select a starting material and a series of reagents necessary to synthesize this compound in as few steps as possible. Enter your selection as a number for the starting material, followed by the letters of the reagents, in the order that you wish to use them, i.e. 3abcf.

You are employed as a coop student at the Drug and Alcohol Testing Association of Canada (DATAC) developing analytical tests for sports doping agents. You are asked to prepare a procedure for the extraction of methylphenidate, the active compound in Ritalin, from urine samples (consider them as simple aqueous layers, you do not need to consider other components!). The goal of the procedure is to extract the methylphenidate into an organic layer which will then be evaporated, and the residue will be tested for the drug.Your colleague is helping you develop the urine test. They suggest that the urine should be adjusted to a pH above 7 before extracting with the organic solvent. Why is this necessary? Support your explanation with a full arrow-pushing mechanism for the reaction that would occur if the pH was below 7. Include all formal charges, intermediates (if applicable) and products.

You are employed as a coop student at the Drug and Alcohol Testing Association of Canada (DATAC) developing analytical tests for sports doping agents. You are asked to prepare a procedure for the extraction of methylphenidate, the active compound in Ritalin, from urine samples (consider them as simple aqueous layers, you do not need to consider other components!). The goal of the procedure is to extract the methylphenidate into an organic layer which will then be evaporated, and the residue will be tested for the drug.You find that methylphenidate is highly soluble in 2-methyltetrahydrofuran, a bio-renewable solvent. Draw the structure of 2-methyltetrahydrofuran and give two reasons why it is a good solvent choice for liquid-liquid extraction.

What is the theoretical yield and limiting reagent for the reaction of benzophenone with sodium borohydride to form diphenyl methanol as described in the experiment provided if you begin with 1.75g of benzophenone in 25 mL of 95% ethanol and add 0.75 g of sodium borohydride portion wise over 45 minutes?

using 0.0015 moles benzaldehyde and 0.0015 moles (carbethoxymethylene) triphenylphosphine  Use 0.15 grams as experimental yield and calculate theoretical and percent yield  show all steps

please solve question 1 and 2, thanks alot sir for ur help, note that this is not a graded question, its a past paper

Draw the structure of the major organic product you would expect from the reaction of 1-bromopropane with Nal. You do not have to explicitly draw H atoms. • Draw only the product derived from 1-bromopropane. Do not draw other organic by-products.

I need help with understanding these questions. These questions are not writing/researching responses.

What factors during the experiment caused the percent yield to be different than 100%? What impurities may be present in the final product (look at the spectroscopic data for evidence of this), and how does that effect the percent yield calculation? I got 64% for the percent yield.

The theoretical yield of 1-methylcyclohexene in moles(from 2-methylcyclohexanol amount of 2.239 gram).  The theoretical yield of 1-methylcyclohexene in moles is 0.01961. 1. What is the corrected actual yield(% Relative Area for 1-methylcyclohexene is 82.81%)? The theoretical yield of 1-methylcyclohexene in moles is 0.01961. 2. . What is the calculation of the %yield of 1-methylcyclohexene?

Checking my answer, there was difference with solution. (organic chemistry smith 5th ed 2.47P (d)) Solution said 'the acid base reaction between pentyne and ammonia is product way because pka of pentyne is 25, ammonia is 38 so pentyne will be deprotanted by ammonia.'  but I think (and as written in the book) NH4+ is stronger acid than pentyne and acid-base reaction works when reactant is stronger acid than product conjugate acid. It isn't match that pentyne makes NH4+. who is incorrect?

An organic chemistry laboratory Extraction; the extraction of crude naphtalene- benzoic acid mixture. Naphthalene is a suspect carcinogen and is toxic to aquatic life. Find an alternative pair of molecules that adhere better to the principles of green chemistry and can be separated by extraction using green' solvents. (kindly answer fully)

help please answer in text form with proper workings and explanation for each and every part and steps with concept and introduction no AI no copy paste remember answer must be in proper format with all working

Suppose you took your two compounds, dissolved them in tertbutyl methyl ether and then added them to a separatory funnel.  Now suppose you add in aqueous sodium bicarbonate and vigorusly shake the contents of the separatory funnel. ethanol will be dissolved in tert butyl methyl ether ether and valeric acid will be dissolved in the aqueous sodium bicarbonate layer. Draw the EXACT chemical structure that will exist in each of the layers after shaking with sodium bicarbonate.  (Is it neutral or charged?)

Ee.83.

..) Fill in the blanks with the NAME and STRUCTURE of the ORGANIC REACTANT or the NAME and STRUCTURE of the MAJOR ORGANIC PRODUCT in the following reactions: Fused KOH, 200°C A. 2,2-dichloroheptane -x ? (name, str) Hydroboration В. ? --< Hexanal CH3CH2CH2CH2CH2CHO (name, str) C. ? (name, str) --Оз, НгО-- --X Butanoic acid CH3CH2CH2COOH NANH2, 150°C D. 1,2-dichlorobutane -X ?(name, str)

Calculate theoretical yield of the Grignard reaction synthesis of triphenylmethanol from bromobenzene. Amounts of products used are listed in the image.