Chapter 9, Problem 9.8P

Derive the rate laws for the following enzymatic reactions and sketch and compare, where possible, with the plots shown in Figure E9-2.1.

1. (a) E + S ⇄ E · S ⇄ P + E
2. (b) E + S ⇄ E · S ⇄ E · P → P + E
3. (c) E + S₁ ⇄ E · S₁

   E · S₁ + S₂ ⇄ E · S₁S₂

   E · S₁S₂ → P + E

4. (d) E + S ⇄ E · S → P

   P + E ⇄ E · P

5. (e) Which of the reactions (a) through (d), if any, lend themselves to analysis by a Lineweaver–Burk plot?