Chapter 9, Problem 36P

Summary Introduction

To analyze:

The six nucleotides prior to the start codon and the first nucleotide after the start codon in eukaryotes exhibit strong sequence conservation as determined by the percentage of nucleotides in the $\text{-6 to -1}$ positions and the $\text{+4}$ position (See problem $\text{34}$). Use the data given in the table for problem $\text{35}$ to determine the seven nucleotides that most commonly surround the start in vertebrates.

Introduction:

Consensus sequences are the short stretch of DNA sequences that are commonly located nucleotides found at a specific location of DNA and RNA or amino acids. These sequences are used for inter or intramolecular interactions. These sequences are similar to structure and functions in all organisms. The consensus sequence is a calculated order that states the most frequent nucleotide at that position in the alignment.