Table-C contains DNA-sequence information compiled by Marilyn Kozak ( 1987 ). The data consists of the percentage of A, C, G and T at each position among the 12 nucleotides preceding the start codon in 699 genes from various vertebrate species and at the first nucleotide after the start codon.(The start codon occupies positions + 1 to +3 , and the first nucleotide immediately after the start codon occupies +4 ).Use the data to conclude the consensus order for the 13 nucleotides ( -12 to -1 and +4 ) surrounding the start codon in vertebrate genes. Introduction: Consensus sequences are a short stretch of DNA sequences that are commonly located nucleotides found at a specific location of DNA and RNA. These sequences are used for inter or intramolecular interactions. These sequences are similar in structure and function in all organisms. The consensus sequence is a calculated order that states the most frequent nucleotide at that position in the alignment.

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Chapter 9, Problem 34P

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Table-C contains DNA-sequence information compiled by Marilyn Kozak (1987). The data consists of the percentage of A, C, G and T at each position among the 12 nucleotides preceding the start codon in 699 genes from various vertebrate species and at the first nucleotide after the start codon.(The start codon occupies positions +1 to +3, and the first nucleotide immediately after the start codon occupies +4).Use the data to conclude the consensus order for the 13 nucleotides (-12 to -1 and +4) surrounding the start codon in vertebrate genes.

Introduction:

Consensus sequences are a short stretch of DNA sequences that are commonly located nucleotides found at a specific location of DNA and RNA. These sequences are used for inter or intramolecular interactions. These sequences are similar in structure and function in all organisms. The consensus sequence is a calculated order that states the most frequent nucleotide at that position in the alignment.

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