Chapter 7.8, Problem 19PTS

(a)

Interpretation Introduction

Interpretation:

For the given reaction, which base is suitable to accomplish the desired transformation has to be identified.

Concept Introduction:

Elimination Reaction: It is just reverse reaction of addition where substituent from the given molecule is removed via E1 (the reaction depends only on the substrate involved in the reaction) or E2 (the reaction depends on both of the substituents in the reaction) mechanism.

• Elimination reaction: In elimination reaction, two substituents are removed from the substrate to give the product in presence of base. Elimination reactions are two types, $E1$ and $E2$.
• $E1$ reaction: elimination follows stepwise mechanism.
• $E2$ reaction: elimination follows concerted pathway of mechanism.
• Elimination of compound in presence of bulky base leads to less substituted alkene, in presence of strong base (not bulky) leads to more substituted alkene.

(b).

Interpretation Introduction

Interpretation:

For the given reaction, which base is suitable to accomplish the desired transformation has to be identified.

Concept introduction:

Elimination Reaction: It is just reverse reaction of addition where substituent from the given molecule is removed via E1 (the reaction depends only on the substrate involved in the reaction) or E2 (the reaction depends on both of the substituents in the reaction) mechanism.

• Elimination reaction: In elimination reaction, two substituents are removed from the substrate to give the product in presence of base. Elimination reactions are two types, $E1$ and $E2$.
• $E1$ reaction: elimination follows stepwise mechanism.
• $E2$ reaction: elimination follows concerted pathway of mechanism.
• Elimination of compound in presence of bulky base leads to less substituted alkene, in presence of strong base (not bulky) leads to more substituted alkene.