Student Solutions Manual for Oxtoby/Gillis/Butler's Principles of Modern Chemistry, 8th
8th Edition
ISBN: 9798214170251
Author: David W. Oxtoby, H. Pat Gillis and Laurie J. Butler
Publisher: Cengage Learning US
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Chapter 7, Problem 4P
A gaseous
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need help please and thanks dont understand only need help with C-F
Learning Goal:
As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.
The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7).
Part A - Difference in binding free eenergies
Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol.
The margin of error is 2%.
Part B - Compare difference in free energy to the thermal…
Please correct answer and don't used hand raiting
need help please and thanks dont understand a-b
Learning Goal:
As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.
The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7).
Part A - Difference in binding free eenergies
Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol.
The margin of error is 2%.
Part B - Compare difference in free energy to the thermal energy
Divide the…
Chapter 7 Solutions
Student Solutions Manual for Oxtoby/Gillis/Butler's Principles of Modern Chemistry, 8th
Ch. 7 - Prob. 1PCh. 7 - Is it possible for a motor fuel to have a negative...Ch. 7 - A gaseous alkane is burned completely in oxygen....Ch. 7 - A gaseous alkyne is burned completely in oxygen....Ch. 7 - Write a chemical equation involving structural...Ch. 7 - Prob. 6PCh. 7 - Prob. 7PCh. 7 - Prob. 8PCh. 7 - Prob. 9PCh. 7 - Prob. 10P
Ch. 7 - Prob. 11PCh. 7 - Prob. 12PCh. 7 - Prob. 13PCh. 7 - State the hybridization of each of the carbon...Ch. 7 - Prob. 15PCh. 7 - Prob. 16PCh. 7 - Prob. 17PCh. 7 - In a recent year, the United States produced...Ch. 7 - Prob. 19PCh. 7 - Prob. 20PCh. 7 - Prob. 21PCh. 7 - Prob. 22PCh. 7 - Prob. 23PCh. 7 - Prob. 24PCh. 7 - Prob. 25PCh. 7 - Prob. 26PCh. 7 - Acetic acid can be made by the oxidation of...Ch. 7 - Acrylic fibers are polymers made from a starting...Ch. 7 - Compare the bonding in formic acid (HCOOH) with...Ch. 7 - Prob. 30PCh. 7 - Prob. 31PCh. 7 - Prob. 32PCh. 7 - Prob. 33PCh. 7 - Prob. 34PCh. 7 - Prob. 35PCh. 7 - Describe the changes in hydrocarbon structure and...Ch. 7 - trans-Cyclodecene boils at 193C, but...Ch. 7 - Prob. 38APCh. 7 - Prob. 39APCh. 7 - Consider the following proposed structures for...Ch. 7 - Prob. 41APCh. 7 - Prob. 42APCh. 7 - Prob. 43APCh. 7 - Prob. 44APCh. 7 - Prob. 45APCh. 7 - The steroid stanolone is an androgenic steroid (a...Ch. 7 - The structure of the molecule cyclohexene is Does...Ch. 7 - Prob. 48CP
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