Bundle: Biology: The Unity and Diversity of Life, Loose-leaf Version, 14th + LMS Integrated for MindTap Biology, 2 terms (12 months) Printed Access Card
14th Edition
ISBN: 9781305775480
Author: Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher: Cengage Learning
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 7, Problem 1DAA
Mitochondrial Abnormalities in Tetralogy of Fallot Tetralogy of Fallot (TF) is a genetic disorder in which heart malformations result in abnormal blood circulation, so oxygen does not reach body cells as it should. With insufficient oxygen to accept electrons at the end of miotchondrial electron transfer chains, too many free radicals form. This damages the mitochondria—and the cells. In 2004, Sarah Kuruvilla studied mitochondria in the heart muscle of TF patients. Some of her results are shown in FIGURE 7.13.
| Patient (age) | SPO2(%) | Mitochondrial Abnormalities in TF | |||
| Number | Shape | Size | Broken | ||
| 1(5) | 55 | + | + | − | − |
| 2(3) | 69 | + | + | − | − |
| 3(22) | 72 | + | + | − | − |
| 4(2) | 74 | + | + | − | − |
| 5(3) | 76 | + | + | − | + |
| 6(2.5) | 78 | + | + | − | + |
| 7(1) | 79 | + | + | − | − |
| 8(12) | 80 | + | − | + | − |
| 9(4) | 80 | + | + | − | − |
| 10(B) | 83 | + | − | + | − |
| 11(20) | 85 | + | + | − | − |
| 12(2.5) | 89 | + | − | + | − |
FIGURE 7.13 Mitochondrial changes in tetralogy of Fallot (TF).
(A) Normal heart muscle. Many mitochondria between the fibers provide muscle cells with ATP for contraction. (B) Heart muscle from a person with TF has swollen, broken mitochondria.
(C) Types of mitochondrial abnormalities in TF patients. SPO2 is oxygen saturation of the blood. A normal value of SPO2 is 96%. Abnormalities are marked +.
1. In this study, which abnormality was most strongly associated with TF?
Expert Solution & Answer
Trending nowThis is a popular solution!
Students have asked these similar questions
Molecular Biology Question:
Please help. Thank you
Is Southern hybridization's purpose detecting specific nucleotide sequences? How so?
Use the following information to answer the question(s) below.
Martin Wikelski and L. Michael Romero (Body size, performance and fitness in Galápagos marine iguanas, Integrative and
Comparative Biology 43 [2003]:376-86) measured the snout-to-vent (anus) length of Galápagos marine iguanas and observed
the percent survival of different-sized animals, all of the same age. The graph shows the log snout-vent length (SVL, a
measure of overall body size) plotted against the percent survival of these different size classes for males and females.
Survival (%)
100-
80-
60-
40-
20-
0+
1.9
T
2 2.1
2.2 2.3 2.4 2.5 2.6 2.7
Log SVL (mm)
19) Examine the figure above. What type of selection for body size appears to be occurring in these marine iguanas?
A) directional selection
B) stabilizing selection
C) disruptive selection
D) You cannot determine the type of selection from the above information.
3
24) Use the following information to answer the question below.
Researchers studying a small milkweed population note that some plants produce a toxin and other plants do not.
They identify the gene responsible for toxin production. The dominant allele (T) codes for an enzyme that makes
the toxin, and the recessive allele (t) codes for a nonfunctional enzyme that cannot produce the toxin.
Heterozygotes produce an intermediate amount of toxin. The genotypes of all individuals in the population are
determined (see table) and used to determine the actual allele frequencies in the population.
TT
0.49
Tt
0.42
tt
0.09
Refer to the table above. Is this population in Hardy-Weinberg equilibrium?
A) Yes.
C) No; there are more homozygotes than expected.
B) No; there are more heterozygotes than expected.
D) It is impossible to tell.
Chapter 7 Solutions
Bundle: Biology: The Unity and Diversity of Life, Loose-leaf Version, 14th + LMS Integrated for MindTap Biology, 2 terms (12 months) Printed Access Card
Ch. 7 - Is the following statement true or false? Unlike...Ch. 7 - Glycolysis starts and ends in the ___. a. nucleus...Ch. 7 - Which of the following metabolic pathways...Ch. 7 - Which molecule does not form during glycolysis? a....Ch. 7 - Prob. 5SQCh. 7 - Which of the following reaction pathways is not...Ch. 7 - Prob. 7SQCh. 7 - Prob. 8SQCh. 7 - Prob. 9SQCh. 7 - Mitochondrial Abnormalities in Tetralogy of Fallot...
Ch. 7 - Mitochondrial Abnormalities in Tetralogy of Fallot...Ch. 7 - Mitochondrial Abnormalities in Tetralogy of Fallot...Ch. 7 - Prob. 10SQCh. 7 - Most of the energy that aerobic respiration...Ch. 7 - Prob. 12SQCh. 7 - Prob. 13SQCh. 7 - Prob. 14SQCh. 7 - Match the term with the best description. _____...Ch. 7 - Prob. 1CTCh. 7 - As you learned, membranes impermeable to hydrogen...Ch. 7 - Prob. 3CT
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- 30) A B CDEFG Refer to the accompanying figure. Which of the following forms a monophyletic group? A) A, B, C, and D B) C and D C) D, E, and F D) E, F, and Garrow_forwardMolecular Biology Question. Please help with step solution and explanation. Thank you: The Polymerase Chain Reaction (PCR) reaction consists of three steps denaturation, hybridization, and elongation. Please describe what occurs in the annealing step of the PCR reaction. (I think annealing step is hybridization). What are the other two steps of PCR, and what are their functions? Next, suppose the Tm for the two primers being used are 54C for Primer A and 67C for Primer B. Regarding annealing step temperature, I have the following choices for the temperature used during the annealing step:(a) 43C (b) 49C (c) 62C (d) 73C Which temperature/temperatures should I choose? What is the corresponding correct explanation, and why would I not use the other temperatures? Have a good day!arrow_forwardUsing the data provided on the mean body mass and horn size of 4-year-old male sheep, draw a scatterplot graph to examine how body mass and horn size changed over time.arrow_forward
- Please write a 500-word report about the intake of saturated fat, sodium, alcoholic beverages, or added sugar in America. Choose ONE of these and write about what is recommended by the Dietary Guidelines for Americans (guideline #4) and why Americans exceed the intake of that nutrient. Explain what we could do as a society and/or individuals to reduce our intake of your chosen nutrient.arrow_forwardWrite a 500-word report indicating how you can change the quantity or quality of TWO nutrients where your intake was LOWER than what is recommended by the Dietary Guidelines for Americans and/or the DRIs. Indicate how the lack of the nutrient may affect your health. For full credit, all of the following points must be addressed and elaborated on in more detail for each nutrient: The name of the nutrient At least 2 main functions of the nutrient (example: “Vitamin D regulates calcium levels in the blood and calcification of bones.”) Your percent intake compared to the RDA/DRI (example “I consumed 50% of the RDA for vitamin D”) Indicate why your intake was below the recommendations (example: “I only had one serving of dairy products and that was why I was below the recommendations for vitamin D”) How would you change your dietary pattern to meet the recommendations? – be sure to list specific foods (example: “I would add a yogurt and a glass of milk to each day in order to increase my…arrow_forwardWhy are nutrient absorption and dosage levels important when taking multivitamins and vitamin and mineral supplements?arrow_forward
- I'm struggling with this topic and would really appreciate your help. I need to hand-draw a diagram and explain the process of sexual differentiation in humans, including structures, hormones, enzymes, and other details. Could you also make sure to include these terms in the explanation? . Gonads . Wolffian ducts • Müllerian ducts . ⚫ Testes . Testosterone • Anti-Müllerian Hormone (AMH) . Epididymis • Vas deferens ⚫ Seminal vesicles ⚫ 5-alpha reductase ⚫ DHT - Penis . Scrotum . Ovaries • Uterus ⚫ Fallopian tubes - Vagina - Clitoris . Labia Thank you so much for your help!arrow_forwardRequisition Exercise A phlebotomist goes to a patient’s room with the following requisition. Hometown Hospital USA 125 Goodcare Avenue Small Town, USAarrow_forwardI’m struggling with this topic and would really appreciate your help. I need to hand-draw a diagram and explain the process of sexual differentiation in humans, including structures, hormones, enzymes, and other details. Could you also make sure to include these terms in the explanation? • Gonads • Wolffian ducts • Müllerian ducts • Testes • Testosterone • Anti-Müllerian Hormone (AMH) • Epididymis • Vas deferens • Seminal vesicles • 5-alpha reductase • DHT • Penis • Scrotum • Ovaries • Uterus • Fallopian tubes • Vagina • Clitoris • Labia Thank you so much for your help!arrow_forward
- I’m struggling with this topic and would really appreciate your help. I need to hand-draw a diagram and explain the process of sexual differentiation in humans, including structures, hormones, enzymes, and other details. Could you also make sure to include these terms in the explanation? • Gonads • Wolffian ducts • Müllerian ducts • Testes • Testosterone • Anti-Müllerian Hormone (AMH) • Epididymis • Vas deferens • Seminal vesicles • 5-alpha reductase • DHT • Penis • Scrotum • Ovaries • Uterus • Fallopian tubes • Vagina • Clitoris • Labia Thank you so much for your help!arrow_forwardOlder adults have unique challenges in terms of their nutrient needs and physiological changes. Some changes may make it difficult to consume a healthful diet, so it is important to identify strategies to help overcome these obstacles. From the list below, choose all the correct statements about changes in older adults. Select all that apply. Poor vision can make it difficult for older adults to get to a supermarket, and to prepare meals. With age, taste and visual perception decline. As people age, salivary production increases. In older adults with dysphagia, foods like creamy soups, applesauce, and yogurt are usually well tolerated. Lean body mass increases in older adults.arrow_forwardWhen physical activity increases, energy requirements increase also. Depending on the type, intensity, and duration of physical activity, the body’s requirements for certain macronutrients may change as well. From the list below, choose all the correct statements about the effects of increased physical activity or athletic training. Select all that apply. An athlete who weighs 70 kg (154 lb) should consume 420 to 700 g of carbohydrate per day. How much additional energy an athlete needs depends on the specific activity the athlete engages in and the frequency of the activity. Those participating in vigorous exercise should restrict their fat intake to less than 15%% of total energy intake. Athletes who are following energy-restricted diets are at risk for consuming insufficient protein. The recommendation to limit saturated fat intake to less than 10%% of total energy intake does not apply to athletes or those who regularly engage in vigorous physical activity.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning
Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning
Biology: The Unity and Diversity of Life (MindTap...BiologyISBN:9781305073951Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa StarrPublisher:Cengage Learning
Biology: The Dynamic Science (MindTap Course List)BiologyISBN:9781305389892Author:Peter J. Russell, Paul E. Hertz, Beverly McMillanPublisher:Cengage Learning
Anatomy & PhysiologyBiologyISBN:9781938168130Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark WomblePublisher:OpenStax College
Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
Biology: The Unity and Diversity of Life (MindTap...
Biology
ISBN:9781305073951
Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher:Cengage Learning
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Cengage Learning
Anatomy & Physiology
Biology
ISBN:9781938168130
Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher:OpenStax College
Biology (MindTap Course List)
Biology
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Cengage Learning
Anaerobic Respiration; Author: Bozeman Science;https://www.youtube.com/watch?v=cDC29iBxb3w;License: Standard YouTube License, CC-BY