Campbell Biology: Concepts & Connections (8th Edition)
8th Edition
ISBN: 9780321885326
Author: Jane B. Reece, Martha R. Taylor, Eric J. Simon, Jean L. Dickey, Kelly A. Hogan
Publisher: PEARSON
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Chapter 6, Problem 17TYK
Explain how the mechanism of brown fat
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Which of the following statements concerning gluconeogenesis is NOT true?
a.
Gluconeogenesis is to make glucose from glycogen.
b.
Many of the reactions of gluconeogenesis are glycolytic reactions going in reverse.
c.
The process of gluconeogenesis consumes ATP.
d.
The process of gluconeogenesis is regulated by ATP.
e.
Gluconeogenesis maintains the blood glucose level long after all dietary glucose has been absorbed and oxidized.
Which of the following reactions would be inhibited in the presence of large amounts of an egg white protein that binds and sequesters biotin?
a. Pyruvate to Lactate
b. Pyruvate to Alanine
c. Phosphoenolpyruvate to Pyruvate
d. Pyruvate to oxaloacetate
Can you answer all the parts to following question, true or false:
Q23:
A: The breakdown of a fatty acid produces more energy than the breakdown of glucose (True or False)
B: Acetyl-CoA can be directly converted to pyruvate through the TCA (True or False)
C: Glucagon stimulates the liver to store energy by performing glycolysis (True or False)
D: The keto diet is dangerous due to the risk of developing ketoacidosis (True or False)
Chapter 6 Solutions
Campbell Biology: Concepts & Connections (8th Edition)
Ch. 6 - Fill in the blanks in this summary map to help you...Ch. 6 - A biochemist wanted to study how various...Ch. 6 - In glycolysis, _____ is oxidized and _____ is...Ch. 6 - Which of the following is the most immediate...Ch. 6 - Which of the following is a true distinction...Ch. 6 - The poison cyanide binds to an electron carrier...Ch. 6 - In which of the following is the first molecule...Ch. 6 - Which of the three stages of cellular respiration...Ch. 6 - Compare and contrast fermentation as it occurs in...Ch. 6 - Prob. 10TYK
Ch. 6 - Prob. 11TYKCh. 6 - Prob. 12TYKCh. 6 - In the citric acid cycle, an enzyme oxidizes...Ch. 6 - ATP synthase enzymes are found in the prokaryotic...Ch. 6 - 15. SCIENTIFIC THINKING Several studies have found...Ch. 6 - For a short time in the 1930s, some physicians...Ch. 6 - Explain how the mechanism of brown fat metabolism...
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- Explain the function of brown fat. What does its mechanism imply about the effect of ATP concentrations on the rate of cell respiration?arrow_forwardYou are studying energy production and metabolic activities of prostate cancer cells in the lab. You compare energy metabolism in these cancer cells with normal cells. Which of the following would you observe? Select all that apply Oxidative phosphorylation is reduced in cancer cells compared to normal cells Glycolysis is reduced in cancer cells compared to normal cells Oxidative phosphorylation is enhanced in cancer cells compared to normal cells Glycolysis is enhanced in cancer cells compared to normal cellsarrow_forwardAfter infection, some T cells (a particular type of immune cell) may persist as memory T cells (TMcells). When they re-encounter the same pathogen, TM cells rapidly divide to produce more T cells to help fight off the infection. This rapid cell division requires substantial energy. One way that this energy is provided to TMcells is via increased activity of the ETC. One standard type of experiment for analyzing oxidative metabolism is measuring the oxygen consumption rate OCR in the presence of different compounds. The lines indicate the time at which the different ETC/OxPhos inhibitors were added. Note that the inhibitors are never removed. Complete the table below. Time Period 1 2 3 4 Inhibitor added None Oligomycin (inhibits ATP Synthase) FCCP (Uncoupler) Rotenone + Antimycin (Complexes I and III) Can electrons flow? If so, from which compound to which compound? If not, what is preventing it? Can H+move through the membrane? If so,…arrow_forward
- It has been hypothesized that a diet heavy in sugar may lead to a condition known as non-alcoholic fatty liver disease. Explain?arrow_forwardIn hepatocytes, the enzyme glucokinase catalyzes the ATP-coupled phosphorylation of glucose. Glucokinase binds both ATP and glucose, forming a glucose-ATP-enzyme complex. The enzyme then transfers the phosphoryl group directly from ATP to glucose. Select the advantages of phosphoryl group transfer compared to hydrolysis and subsequent phosphorylation? Glucokinase increases the transition state energy, favoring glucose phosphorylation. Reaction intermediates do not need to be present in excess. The process takes advantage of the high phosphoryl group transfer potential of ATP. ATP hydrolysis is thermodynamically unfavorable compared to group transfer.arrow_forwardThe bodies of humans and other mammals store triglycerides in two kinds of tissue, which are called white and brown fat. The main function of white fat is to store triglycerides for energy. Brown tissue has more mitochondria than white tissue, and these are used to generate body heat in an unusual process. Mitochondria in brown fat make thermogenin, a protein that uncouples ATP synthesis from mitochondrial electron transfer chains. Thermogenin is a transport protein that allows hydrogen ions to move directly across the inner mitochondrial membrane instead of through ATP synthase. Since ATP synthase isn't activated, these "leaky" membranes produce less ATP. However, electrons still pass through electron transfer chains, and this process generates heat. In 2015, Daniele Barbato and his colleagues investigated the effect of a high-fat diet on brown fat mitochondrial function in mice. They maintained an experimental group of mice on a high-fat diet (HFD, 60% fat), and a control group…arrow_forward
- Glucose can be made from oxaloacetate during gluconeogenesis, but if oxaloacetate concentrations are decreased,what other substance can be used to make glucose? How might this contribute to increased fat loss?arrow_forwardWhich of the following steps does NOT require ATP? O A. Conversion of glucose to glucose 6-phosphate O B. Conversion of malate to pyruvate O C. Conversion of pyruvate to oxaloacetate O D. Activation of hormone sensitive lipase by PKA O E. Inactivation of glycogen synthase by PKA is an intermediate metabolite linkage between carbohydrate and fat metabolism. O A. Malate O B. Oxaloacetate OC. Glucose 6-P O D. Acetyl COA O E. Malonyl COAarrow_forwardThe products of glycolysis are broken down in the mitochondria to make more ATP True or False?arrow_forward
- Which of the following statements about glucose metabolism is correct? * Red blood cells can catalyse aerobic glycolysis because they contain oxygen bound to haemoglobin. Fructose cannot be used for gluconeogenesis in the liver. Glycolysis can proceed in the absence of oxygen only if pyruvate is formed from lactate in muscle. All of the reactions of glycolysis are freely reversible for gluconeogenesis. Red blood cells can only metabolise glucose by anaerobic glycolysis and the pentose phosphate pathway.arrow_forwardListed are some hypothetical medical conditions, describe their effect on cellular respiration (specifically refer to the effect they will have on energy production). a) A person is unable to take glucose into their cells. b) A mutation occurs in the ATP synthase protein and it is inactive. c) The mitochondrial inner membrane is very permeable to H+.arrow_forwardHow does a ketogenic diet decrease the level of urea in obese patients and increase the level of creatine in obese patients? (explain on a molecular level)arrow_forward
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