Chapter 5, Problem 5.7PS

(a)

Summary Introduction

To determine and explain: The value of $\Delta G°\text{'}$ for steady-state concentration of 3-phosphoglycerate and 2-phosphoglycerate in human red blood cells as $61\mu M\text{and}4.3\mu M$ respectively. When given that K’_eq for their inter-conversion reaction is 0.165 at 25^oC and 7.0 pH value.

Introduction: Free energy of a system is that amount of energy that is used can be changed into work in a system provided that the temperature and pressure of the system remain the same. It is denoted by $\Delta G$ . Free energy is informative of the extent to which a reaction can proceed so that all the reactants and products can reach a concentration value of 1.0 M when the conditions are maintained the standard.

(b)

Summary Introduction

To determine and explain: The value of $\Delta G\text{'}$ for steady-state concentration of 3-phosphoglycerate and 2-phosphoglycerate in human red blood cells as $61\mu M\text{and}4.3\mu M$ respectively. When given that K’_eq for their inter-conversion reaction is 0.165 at 25^oC and pH value 7.0 explaining the difference in values of $\Delta G\text{'}$ and $\Delta G°\text{'}$

Introduction:  Free energy of a system is that amount of energy that is used can be changed into work in a system provided that the temperature and pressure of the system remain the same. It is denoted by $\Delta G$ . Free energy is informative of the extent to which a reaction can proceed so that all the reactants and products can reach a concentration value of 1.0 M when the conditions are maintained the standard.

(c)

Summary Introduction

To determine: How high can the 2PG concentration before the given reaction stops due to thermodynamic instability if the conditions in the cell changes such that the concentration of 3PG remains at $61\mu M$ but the concentration of 2PG rises.

Introduction: Free energy of a system is that amount of energy that is used can be changed into work in a system provided that the temperature and pressure of the system remain the same. It is denoted by $\Delta G$ . Free energy is informative of the extent to which a reaction can proceed so that all the reactants and products can reach a concentration value of 1.0 M when the conditions are maintained the standard.