Prescott's Microbiology
Prescott's Microbiology
10th Edition
ISBN: 9781259281594
Author: Joanne Willey, Linda Sherwood Adjunt Professor Lecturer, Christopher J. Woolverton Professor
Publisher: McGraw-Hill Education
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Chapter 5, Problem 3CHI
Summary Introduction

The nucleus is one of the largest organelles in the cell and that contains chromosomes. Eukaryotic chromosomes are composed of a complex of DNA and protein structure is known as chromatin. The chromatin structure serves for the packing and condensation of DNA molecules, thereby; the large size of DNA molecules can be inserted into the cell. There are five histone proteins are found in eukaryotes such as H1, H2A, H2B, H3, and H4. Eight molecules of histones create a structure called an ellipsoid containing 11 nm in long and 6.5-7 nm in diameter. The DNA wraps around the ellipsoid and produces a “beads on a string” formation. Each bead is known as a nucleosome. The highly compacted structure of the chromosome is found during cell division. Histones proteins and other molecules, mainly contribute to the compact structure of chromosomes.

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Which is the expected outcome following the deacetylation of histones? a) Coiling of chromatin, preventing it from being accessed by transcriptional machinery b) Coiling of chromatin, allowing it to be accessed by transcriptional machinery c) Uncoiling of chromatin, preventing it from being accessed by transcriptional machinery d) Uncoiling of chromatin, allowing it to be accessed by transcriptional machinery
Since eukaryotic chromosomes are assembled with histone proteins, how are replication and transcription carried out? Describe the mechanisms.
Which histone is not a necessary component in the formation of nucleosornes?
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