Biology
12th Edition
ISBN: 9781260494570
Author: Raven, Peter
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 5, Problem 1S
figure 5.5 describes a classic experiment demonstrating the ability of proteins to move within the plane of the cell’s plasma membrane. The following table outlines three different experiments using the fusion of labeled mouse and human cells.
| Experiment Conditions | Temperature (°C) Result |
| 1 Fuse human and mouse cells | 37 Intermixed membrane proteins |
| 2 Fuse human and mouse cells in presence of ATP inhibitors | 37 Intermixed membrane proteins |
| 3 Fuse human and mouse cells | 4 No intermixing of membrane proteins |
What conclusions can you reach about the movement of these proteins?
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Experiment I: Scientists took two types of human epithelial cells and placed them in an experimental
system that could measure intracellular (IN) and extracellular concentration (OUT) of 3 substances: Na+,
ATP and Glucose. Cell type A was nonmutant whereas cell type B had a mutation in a transmembrane
protein. At the beginning, middle and end of the experiment, concentrations were measured for all three
substances as shown below.
Cell type A (non-mutant)
Time
IN [Na+]
0
10 ms
20 ms
Concentration in mM
200
150
100
150mM
25mM
150mM
Q1. Analyze the intracellular concentration changes in the table (above) and the graph (below left).
Label the key at the bottom left. Graph the extracellular concentration changes in this data set using the
graph below right and the same key. With cell image on bottom right, diagram what is happening using
arrows and labels for the transported substance. And finally, at the bottom of the page describe what is
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Chapter 5 Solutions
Biology
Ch. 5.1 - Prob. 1LOCh. 5.1 - Explain the fluid mosaic model of membrane...Ch. 5.2 - List the different components of phospholipids.Ch. 5.2 - Prob. 2LOCh. 5.2 - Prob. 3LOCh. 5.3 - Illustrate the functions of membrane proteins.Ch. 5.3 - Prob. 2LOCh. 5.3 - Prob. 3LOCh. 5.4 - Compare simple diffusion and facilitated...Ch. 5.4 - Prob. 2LO
Ch. 5.4 - Prob. 3LOCh. 5.5 - Prob. 1LOCh. 5.5 - Prob. 2LOCh. 5.5 - Prob. 3LOCh. 5.6 - Distinguish between endocytosis and exocytosis.Ch. 5.6 - Illustrate how endocytosis can be specific.Ch. 5 - According to the fluid mosaic model, membranes are...Ch. 5 - Prob. 2IQCh. 5 - The fluid mosaic model of the membrane describes...Ch. 5 - What chemical property characterizes the interior...Ch. 5 - The transmembrane domain of an integral membrane...Ch. 5 - The specific function of a membrane within a cell...Ch. 5 - The movement of water across a membrane is...Ch. 5 - Prob. 6UCh. 5 - Which of the following is NOT a mechanism for...Ch. 5 - A bacterial cell that can alter the composition of...Ch. 5 - What variable(s) influence(s) whether a nonpolar...Ch. 5 - Which of the following does NOT contribute to the...Ch. 5 - How are active transport and coupled transport...Ch. 5 - A cell can use the process of facilitated...Ch. 5 - figure 5.5 describes a classic experiment...Ch. 5 - Each compartment of the endomembrane system of a...Ch. 5 - The distribution of lipids in the ER membrane is...
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