Biology 2e
Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Chapter 41, Problem 27CTQ

How does the renin-angiotensin-aldosterone mechanism function? Why is it controlled by the kidneys?

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Diagram/flow chart the reactions and interactions of the renin-angiotensin-aldosterone pathway. What conditiion is the primary stimulus for its activation? What would hapen to renin secretion in a patient with chronic kidney failure?
Renin is secreted in response to hypovolemia or to an increase in the osmolality of the blood. Provide three possible mechanisms by which these conditions may stimulate rennin secretion. What are the consequences of increased rennin secretion that lead to increased aldosterone secretion? Present this sequence of events. Why are angiotensin converting enzyme inhibitors (ACEIs) used as a common therapy for hypertension? How do they influence blood pressure? Are plasma levels of renin elevated or depressed in a patient with Conn’s disease? Why?
Describe the renin-angiotensin-aldosterone pathway.

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Biology 2e

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