Prescott's Microbiology
10th Edition
ISBN: 9781259281594
Author: Joanne Willey, Linda Sherwood Adjunt Professor Lecturer, Christopher J. Woolverton Professor
Publisher: McGraw-Hill Education
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Chapter 33.2, Problem 3RIA
Summary Introduction
Many direct factors or general barriers contribute to all host-microbe relationship to some degree. In some conditions, they favor the microbial establishments and in some conditions, they provide some measure of general defense to the host. The vertebral host possesses some specific physical and mechanical barriers. These barriers are the first line of defense against physical, chemical, and microbial assaults. Skin, mucous membranes, epithelia of the respiratory, genitourinary, and gastrointestinal systems are examples of first-line defense barriers.
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The production of antimicrobial peptides is one of the most evolutionarily ancient mechanisms of defense for multicellular organisms, and most eukaryotic species make many different forms of these proteins. For instance, human paneth cells in the gastrointestinal epithelium make 21 different defensins. The reason for this diversity of antimicrobial peptides is:
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Select all of the following that are functions performed by different antibodies.
a) Group of answer choices
b) Attracting natural killer cells to destroy an infected cell.
c) Blocking the ability of a pathogen to bind to a host cell
d) Lysing a pathogen cell wall or lipid bilayer.
e) Marking a pathogen so that innate immune cells destroy the pathogen.
f) Helping complement proteins bind to a pathogen.
Chapter 33 Solutions
Prescott's Microbiology
Ch. 33.1 - Prob. 1RIACh. 33.1 - Compare and contrast the adaptive and innate...Ch. 33.2 - Why is the skin such a good first line of defense...Ch. 33.2 - Prob. 2RIACh. 33.2 - Prob. 3RIACh. 33.3 - What strategies could a Gram-negative bacterium...Ch. 33.3 - Prob. 1.1RIACh. 33.3 - Prob. 1.2RIACh. 33.3 - Prob. 1.3RIACh. 33.3 - Prob. 1.4RIA
Ch. 33.3 - Prob. 1.5RIACh. 33.3 - Prob. 2.1RIACh. 33.3 - Prob. 2.2RIACh. 33.3 - How might acute-phase reactants assist in pathogen...Ch. 33.4 - For what does the dendritic cell use its cellular...Ch. 33.4 - Prob. 2MICh. 33.4 - Describe the structure and function of each of the...Ch. 33.4 - Prob. 1.2RIACh. 33.4 - Prob. 1.3RIACh. 33.4 - What is a plasma cell?Ch. 33.4 - Prob. 2.2RIACh. 33.4 - Discuss the role of NK cells in protecting the...Ch. 33.4 - Prob. 3.1RIACh. 33.4 - Injury to the spleen can lead to its removal. What...Ch. 33.4 - Describe SALT and MALT functions in innate...Ch. 33.5 - Prob. 1RIACh. 33.5 - Prob. 2RIACh. 33.5 - How do macrophages and dendritic cells become...Ch. 33.6 - Prob. 1MICh. 33.6 - Prob. 1RIACh. 33.6 - How does chronic inflammation differ from acute...Ch. 33 - Some pathogens invade cells; others invade tissue...Ch. 33 - How might the various antimicrobial chemical...Ch. 33 - How might a scientist use selective gene knockouts...Ch. 33 - Conservation of resources is a common theme in...
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- Describe four general mechanisms of antimicrobial resistance.arrow_forwardDraw a figure illustrating the sequence of events in a typical inflammatory response to a bacterial infection caused by injury to the skin (in 3 main stages). Include a note at top of figure: Is this an example of an innate response or adaptive immune response? Include the following structures/cells/chemicals: epidermis, dermis, splinter contaminated with bacteria puncturing skin, macrophages, mast cells, neutrophils, nitric oxide (as blue dots), endothelial cells lining capillary, red blood cells within capillary, histamine (as green dots). Under each stage, describe the events occurring in the 3 main stages: Stage 1: What do mast cells and endothelial cells produce in initial response to injury? What do the chemicals produced by the cells do? Stage 2: What happens to capillaries? What leaks out of capillaries to enter the site of the wound? Stage 3: What do neutrophils and macrophages do? What happens to capillaries at this point?arrow_forward4) A patient has their spleen removed due to an accident. How will this affect the immune response? 5) You come in contact with staphylococci through a cut. What cellular features will the immune cells recognize? 6) Name two opsonins and how do these molecules help the immune response? 7) Fever is part of the inflammatory process. What is the role of fever during an immune response? 8) This chemical is used to induce anti-viral responses in cells to protect the cells from viral infections. 9) This complement activation pathway is activated when complement binds to an antibody bound to antigens.arrow_forward
- Toll-like receptors represent an ancient pathogen-recognition system. The first pattern recognition receptor (PRR) important in innate immune responses was discovered in the fruit fly Drosophila melanogaster. Stimulation of this receptor, called Toll, induces: The synthesis of prostaglandins and leukotrienes The inflammatory response in Drosophila hemolymph vessels The production of antimicrobial peptides The recruitment of phagocytic cells to the site of infection The activation of Drosophila complementarrow_forwardList the most important antifungal defenses found in humans.arrow_forwardDescribe in chronological order the steps involved in the recruitment of neutrophils to infected tissue sites during an innate immune response. Use the following terms in your description: rolling adhesion, tight binding, extravasation, migration, inflammatory mediators, integrins, adhesion molecules, chemokines, selectins, sialyl-Lewisx, and basement membrane proteases.arrow_forward
- Which is true regarding the innate immune system? A) O Opsonization is responsible for destroying virus-infected cells. B) OPeyer's patches are part of your adaptive immune system that serves to help in antibody formation C)O Your microbiota consists of billions of bacteria that are found in (and on) every part ofyour body 11 D) O Your innate immune system is generally faster acting than your adaptive immune system. E) O Microbial antagonism the mechanism by which pathogens are able to colonize your bodyarrow_forwardWhat is the role of the immune system in the prevention and treatment of chronic wound infections, and how can understanding the interactions between the host immune response and microbial pathogens lead to the development of more effective therapeutic interventions?arrow_forwardSelect all of the following that are functions performed by different antibodies. ( select all the correct answers) Group of answer choices a) Attracting natural killer cells to destroy an infected cell. b) Blocking the ability of a pathogen to bind to a host cell c) Lysing a pathogen cell wall or lipid bilayer. d) Marking a pathogen so that innate immune cells destroy the pathogen. e) Helping complement proteins bind to a pathogen.arrow_forward
- Identify the major mechanical and chemical defenses that protect internal tissues from microbial attack.arrow_forwardDefine the sequence of events for processing and presentingantigens from both intracellular (endogenous) and extracellular(exogenous) pathogens.arrow_forward1. What phagocytic cells utilize in their membrane to identify phagocytic objects? A) Opsonin receptors B) Fc receptors C) Toll-like receptors D) All of the above E) None of the above. 2. Which is NOT a measure for fighting against viral infections? A). TNF-α B). IFN-Y C). IL-1 D). IL-4 E). All of the above promote anti-viral reactions. 3. Which could be the chain formula for IgA in the mucosa? Α). απλη Β). (μ2λ2)s C). αμκ2 D). μ2K2 E). (α2K2)2arrow_forward
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