Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 30, Problem 14P
Interpretation Introduction
Interpretation:
Based on the following options the most suitable account of peptidyl transfer reaction and its reason should be determined.
(a) The peptidyl-tRNA located within the A site, or
(b) To get the peptidyl chain the aminoacyl-tRNA is moved towards the P site.
Concept Introduction:
Translation is the procedure through which a protein is synthesized from the info confined in a molecule of mRNA or messenger RNA. Translation of an mRNA molecule by the ribosome happens in 3 stages: initiation, elongation, and termination.
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- The Energetic Cost of Peptide Elongation How many ATP equivalents are consumed for each amino acid added to an elongating polypeptide chain during the process of protein synthesis?arrow_forwardOn average, how many phosphoanhydride bonds (P;-P; bonds) are directly hydrolyzed in thecourse of synthesizing a 200 amino acid protein? Assume that you begin with the mature mRNA,ribosomal subunits, tRNAs, free amino acids, and all necessary factors.arrow_forwardAs we focused on the translation of mRNA into proteins as well as on protein structure and function. Along the way, we found many opportunities to consider the methods and reasoning by which much of this informationwas acquired. From the explanations given in the chapter,what answers would you propose to the following fundamentalquestion What experimentally derived information led to Holley’sproposal of the two-dimensional cloverleaf model of tRNA?arrow_forward
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