Commonly used vaccines for influenza are trivalent and contain only one type of influenza B virus. They may be ineffective against other types of influenza B virus. A randomized clinical trial was performed among children 3 to 8 years of age in 8 countries. Children received either a quadrivalent vaccine (QIV) that had more than one influenza B virus or a trivalent Hepatitis A vaccine (control) (Jain, et al., [9]. New England Journal of Medicine 2013: 369(26): 2481–2491). An attack rate (i.e.,% of children who developed influenza) starting 14 days after vaccination until the end of the study was computed for each vaccine group, stratified by age. The following data were reported: Table 3.7 Attack rate for influenza by age and treatment group Suppose 3 children in a village ages 3, 5, and 7 are vaccinated with the QIV vaccine. What is the probability that at least one child among the 3 will get influenza?
Commonly used vaccines for influenza are trivalent and contain only one type of influenza B virus. They may be ineffective against other types of influenza B virus. A randomized clinical trial was performed among children 3 to 8 years of age in 8 countries. Children received either a quadrivalent vaccine (QIV) that had more than one influenza B virus or a trivalent Hepatitis A vaccine (control) (Jain, et al., [9]. New England Journal of Medicine 2013: 369(26): 2481–2491). An attack rate (i.e.,% of children who developed influenza) starting 14 days after vaccination until the end of the study was computed for each vaccine group, stratified by age. The following data were reported: Table 3.7 Attack rate for influenza by age and treatment group Suppose 3 children in a village ages 3, 5, and 7 are vaccinated with the QIV vaccine. What is the probability that at least one child among the 3 will get influenza?
Commonly used vaccines for influenza are trivalent and contain only one type of influenza B virus. They may be ineffective against other types of influenza B virus. A randomized clinical trial was performed among children 3 to 8 years of age in 8 countries. Children received either a quadrivalent vaccine (QIV) that had more than one influenza B virus or a trivalent Hepatitis A vaccine (control) (Jain, et al., [9]. New England Journal of Medicine 2013: 369(26): 2481–2491). An attack rate (i.e.,% of children who developed influenza) starting 14 days after vaccination until the end of the study was computed for each vaccine group, stratified by age. The following data were reported:
Table 3.7 Attack rate for influenza by age and treatment group
Suppose 3 children in a village ages 3, 5, and 7 are vaccinated with the QIV vaccine. What is the probability that at least one child among the 3 will get influenza?
The following are suggested designs for group sequential studies. Using PROCSEQDESIGN, provide the following for the design O’Brien Fleming and Pocock.• The critical boundary values for each analysis of the data• The expected sample sizes at each interim analysisAssume the standardized Z score method for calculating boundaries.Investigators are evaluating the success rate of a novel drug for treating a certain type ofbacterial wound infection. Since no existing treatment exists, they have planned a one-armstudy. They wish to test whether the success rate of the drug is better than 50%, whichthey have defined as the null success rate. Preliminary testing has estimated the successrate of the drug at 55%. The investigators are eager to get the drug into production andwould like to plan for 9 interim analyses (10 analyzes in total) of the data. Assume thesignificance level is 5% and power is 90%.Besides, draw a combined boundary plot (OBF, POC, and HP)
Please provide the solution for the attached image in detailed.
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GISS
Worksheet 10
Jesse runs a small business selling and delivering mealie meal to the spaza shops.
He charges a fixed rate of R80, 00 for delivery and then R15, 50 for each packet of
mealle meal he delivers. The table below helps him to calculate what to charge
his customers.
10
20
30
40
50
Packets of mealie
meal (m)
Total costs in Rands
80
235
390
545
700
855
(c)
10.1.
Define the following terms:
10.1.1. Independent Variables
10.1.2. Dependent Variables
10.2.
10.3.
10.4.
10.5.
Determine the independent and dependent variables.
Are the variables in this scenario discrete or continuous values? Explain
What shape do you expect the graph to be? Why?
Draw a graph on the graph provided to represent the information in the
table above.
TOTAL COST OF PACKETS OF MEALIE MEAL
900
800
700
600
COST (R)
500
400
300
200
100
0
10
20
30
40
60
NUMBER OF PACKETS OF MEALIE MEAL
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, statistics and related others by exploring similar questions and additional content below.
Introduction to experimental design and analysis of variance (ANOVA); Author: Dr. Bharatendra Rai;https://www.youtube.com/watch?v=vSFo1MwLoxU;License: Standard YouTube License, CC-BY