Biology 2e
Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Chapter 3, Problem 14RQ

Cholesterol is an integral part of plasma membranes. Based on its structure, where is it found in the membrane?

  1. on the extracellular surface
  2. embedded with the phospholipid heads
  3. within the tail bilayer
  4. attached to the intracellular surface

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Phospholipids form the main fabric of the plasma membrane. One feature of phospholipids is that when they are placed in an aqueous solution, they will self-assemble into a double layer (bilayer) that resembles the bilayer of the plasma membrane. This self-assembly occurs because phospholipids are hydrophilic at one end (the phospholipid head) and hydrophobic at the other end (the phospholipid tails). Drag the labels to their appropriate locations in the figure. 1. First, drag labels of Group 1 to targets (a) and (b) to indicate whether these environments are hydrophilic or hydrophobic. 2. Next, drag the phospholipid layers (Group 2) to targets (c) and (d) to indicate how they are oriented in the plasma membrane. 3. Finally, drag labels of Group 1 to targets (e), (f), and (g) to indicate which portions of the membrane protein are hydrophilic and which are hydrophobic. Group 1 extracellular hydrophobic fluid © hydrophilic plasma membrane Group 1 Group 2 (f membrane protein Group 1 Group…
Which of the following statements are acceptable and why? [Whereas all the carbohydrate in the plasma membrane faces outward on the external surface of the cell, all the carbohydrate on internal membranes faces toward the cytosol.] [Although lipid molecules are free to diffuse in the plane of the bilayer, they cannot flip-flop across the bilayer unless enzyme catalysts called phospholipid translocators are present in the membrane.]
Phospholipids (Which is charged, what is the functional significance? Are they preferentially located on cytosolic or extracellular lipid monolayer? What is the functional significance of plasma membrane asymmetry?)

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