Organic Chemistry
Organic Chemistry
8th Edition
ISBN: 9781305580350
Author: William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher: Cengage Learning
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Chapter 28.2, Problem 28.3P
Interpretation Introduction

Interpretation:

The Complementary DNA base sequence for 5'-CCGTACGA-3' has to be written.

Concept Introduction:

In Watson - Crick Model of DNA, the DNA molecule consists of a Complementary double helix.  The two DNA strands are anti-parallel to each other and are in right handed helix.  The DNA molecule consists of bases purines and pyrimidines.  The purines are Adenine (A) and Guanine (G) whereas pyrimidines are Cytosine (C) and Thymine (T).  On the complementary DNA strands, the bases are linked together as A-T and G-C.  The base strand of DNA is read from 5' end to 3' end direction whereas the complementary strand is read from 3' end to 5' end direction of the base strand.

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A strand of DNA contains the bases of 5’-T-C-A-G-C-A-T-3’. Give the base sequence on the complementary DNA strand
A strand of DNA contains the base pair 5’-A-C-A-C-T-T-A-A-C-3’. Give the base sequence on the complementary DNA strand
Imagine a single DNA strand containing a section with the following base sequence, 5’-GCATTGGC-3’. What is the base sequence of the complementary strand?
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