Prescott's Microbiology
10th Edition
ISBN: 9781259281594
Author: Joanne Willey, Linda Sherwood Adjunt Professor Lecturer, Christopher J. Woolverton Professor
Publisher: McGraw-Hill Education
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Chapter 27, Problem 7CHI
Associated with the envelope of herpesviruses are numerous proteins called tegument proteins. Upon fusion of the viral envelope with the cell’s plasma membrane, some of the tegument proteins are released into the cytosol. The fate of these proteins is unknown, although many are thought to be degraded. Herpes simplex virus 1 (HSV-1) encodes a tegument protein called vhs. This protein is released into the cytosol as HSV-1 enters the cell, but it is not degraded. The vhs protein has been shown to make cuts in RNA molecules (i.e., it is an endoribonuclease). Suggest a role for vhs in the life cycle of HSV-1. Justify your suggestion.
Read the original paper: Dauber, B., et al. 2011. The Herpes simplex virus 1 vhs protein enhances translation of viral true later mRNAs and virus production in a cell type-dependent manner. J. Virol. 85(11):5363.
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Chapter 27 Solutions
Prescott's Microbiology
Ch. 27.1 - List some characteristics used in classifying...Ch. 27.1 - Consider these terms: Equine torovirus,...Ch. 27.2 - What enzyme found in the T4 baseplate facilitates...Ch. 27.2 - Why do you think T4 evolved to initiate DNA...Ch. 27.2 - What function does HMC glycosylation serve?Ch. 27.2 - How is the envelope of this virus formed? How does...Ch. 27.2 - Explain why the T4 genome is circularly permuted.Ch. 27.2 - Prob. 1.2RIACh. 27.2 - How is a prophage induced to become active again?Ch. 27.2 - Describe the roles of cII, CIII, repressor (CI),...
Ch. 27.2 - How do the temperate phages Mu and P1 differ from...Ch. 27.2 - The CRISPR/Cas system has been a boon to...Ch. 27.2 - Why do cold sores recur throughout the lifetime of...Ch. 27.2 - In what part of the host cell does a herpesvirus...Ch. 27.2 - Many small DNA viruses rely on host enzymes for...Ch. 27.3 - Why is the X174 genome considered plus stranded?Ch. 27.3 - Prob. 2MICh. 27.3 - Why is it necessary for some ssDNA viruses to...Ch. 27.3 - From the point of view of the virus, compare the...Ch. 27.3 - How do parvoviruses trick the host DNA polymerase...Ch. 27.4 - The rotavirus genome encodes 12 proteins. Suggest...Ch. 27.4 - Describe the life cycle of 6 phage. What makes...Ch. 27.4 - Prob. 3RIACh. 27.4 - In what ways are the life cycles of 6 and...Ch. 27.5 - Where in the host does the plus-strand RNA genome...Ch. 27.5 - How do some plus-strand viruses use polyproteins...Ch. 27.5 - What is an IRES? Why is it important?Ch. 27.5 - Prob. 3RIACh. 27.6 - How does that use of a segmented genome by...Ch. 27.6 - Prob. 2RIACh. 27.7 - Prob. 1MICh. 27.7 - Prob. 1RIACh. 27.7 - Prob. 2RIACh. 27.7 - What role does alternative splicing play in the...Ch. 27.8 - Prob. 1RIACh. 27.8 - Trace the HBV multiplication cycle, paying...Ch. 27 - No temperate RNA phages have yet been discovered....Ch. 27 - The choice between lysogeny and lysis is...Ch. 27 - Prob. 3CHICh. 27 - You are studying RNA viruses and have discovered a...Ch. 27 - Prob. 5CHICh. 27 - Upon infection of host epithelial cells,...Ch. 27 - Associated with the envelope of herpesviruses are...
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