Chapter 27, Problem 27.81AP

Interpretation Introduction

(a)

Interpretation:

The structures of two monomethyl esters of $N\text{-acetyl-L-aspartic acid}$ are to be predicted.

Concept introduction:

The chemical compounds in which carbon is bonded with the acidic and basic group along with hydrocarbon side chain are known as amino acids. The amino acids are classified into acidic, basic, polar, non-polar, essential, and non-essential categories. The three-word abbreviation or one-word abbreviation is used for amino acids.

Interpretation Introduction

(b)

Interpretation:

The reason as to why two monomethyl esters of $N\text{-acetyl-L-aspartic acid}$ could be separated by cation-exchange chromatography at $\text{pH}=3.0$ but could not be separated by cation-exchange chromatography at $\text{pH}=7$ is to be stated. The explanation for the corresponding answer is to be stated.

Concept introduction:

Cation-exchange chromatography is a type of separation technique in which anion resin is used in the chromatography column. This anion resin interacts with the cation part of the sample and retards their follow in the column. The neutral compound follows easily on this chromatography column.