ORGANIC CHEMISTRY-PACKAGE >CUSTOM<
ORGANIC CHEMISTRY-PACKAGE >CUSTOM<
10th Edition
ISBN: 9781260028355
Author: Carey
Publisher: MCG CUSTOM
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Chapter 26.6, Problem 10P
Interpretation Introduction

Interpretation:

The standard amino acid that is the biological precursor to γ-butyric acid (4-aminobutanoic acid) which it forms by decarboxylation is to be determined.

Concept Introduction:

Standard amino acids are α-amino acids, that is they have the amine group bonded to the same carbon that is bonded to the carboxylic acid group.

Decarboxylation reaction replaces the COOH group by a hydrogen atom with evolution of the carbon dioxide.

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Predict the reactants used in the formation of the following compounds using Acid-Catalyzed dehydration reaction
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.. Give the major organic product(s) for each of the following reactions or sequences of reactions. Show ll relevant stereochemistry [3 ONLY]. A H Br 1. NaCN 2 NaOH, H₂O, heat 3. H3O+ B. CH₂COOH 19000 1. LiAlH4 THF, heat 2 H₂O* C. CH Br 1. NaCN, acetone 2 H3O+, heat D. Br 1. Mg. ether 3. H₂O+ 2 CO₂ E. CN 1. (CH) CHMgBr, ether 2 H₂O+
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