A retrosynthetic analysis to plan a synthesis of isoleucine from 2-methyl-1-butanol is to be used and equations for the synthesis are to be written. Concept Introduction: Amino acids can be synthesized by the reaction of an aldehyde with NH 4 Cl and NaCN . It is known as the Strecker synthesis. This is a double nucleophilic addition reaction that converts the aldehyde to an amino acid having one more carbon atom. Hydrolysis of the nitrile group converts the nitrile to the carboxylic acid group. Aldehydes can be obtained by the oxidation of primary alcohols with pyridinium chlorochromate. This reagent stops the oxidation at the aldehyde stage.

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Answer 1

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Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 26.4, Problem 7P

Interpretation Introduction

Interpretation:

A retrosynthetic analysis to plan a synthesis of isoleucine from 2-methyl-1-butanol is to be used and equations for the synthesis are to be written.

Concept Introduction:

Amino acids can be synthesized by the reaction of an aldehyde with NH4Cl and NaCN. It is known as the Strecker synthesis.

This is a double nucleophilic addition reaction that converts the aldehyde to an amino acid having one more carbon atom.

Hydrolysis of the nitrile group converts the nitrile to the carboxylic acid group.

Aldehydes can be obtained by the oxidation of primary alcohols with pyridinium chlorochromate. This reagent stops the oxidation at the aldehyde stage.

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Answer 2

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Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 26.4, Problem 7P

Interpretation Introduction

Interpretation:

A retrosynthetic analysis to plan a synthesis of isoleucine from 2-methyl-1-butanol is to be used and equations for the synthesis are to be written.

Concept Introduction:

Amino acids can be synthesized by the reaction of an aldehyde with NH4Cl and NaCN. It is known as the Strecker synthesis.

This is a double nucleophilic addition reaction that converts the aldehyde to an amino acid having one more carbon atom.

Hydrolysis of the nitrile group converts the nitrile to the carboxylic acid group.

Aldehydes can be obtained by the oxidation of primary alcohols with pyridinium chlorochromate. This reagent stops the oxidation at the aldehyde stage.

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Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 26.4, Problem 7P

Interpretation Introduction

Interpretation:

A retrosynthetic analysis to plan a synthesis of isoleucine from 2-methyl-1-butanol is to be used and equations for the synthesis are to be written.

Concept Introduction:

Amino acids can be synthesized by the reaction of an aldehyde with NH4Cl and NaCN. It is known as the Strecker synthesis.

This is a double nucleophilic addition reaction that converts the aldehyde to an amino acid having one more carbon atom.

Hydrolysis of the nitrile group converts the nitrile to the carboxylic acid group.

Aldehydes can be obtained by the oxidation of primary alcohols with pyridinium chlorochromate. This reagent stops the oxidation at the aldehyde stage.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 26.4, Problem 7P

Interpretation Introduction