ORGANIC CHEMISTRY-PACKAGE >CUSTOM<
ORGANIC CHEMISTRY-PACKAGE >CUSTOM<
10th Edition
ISBN: 9781260028355
Author: Carey
Publisher: MCG CUSTOM
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Chapter 26.15, Problem 22P
Interpretation Introduction

Interpretation:

The steps involved in the synthesis of Ala-Leu from alanine and leucine using benzyloxycarbonyl and benzyl ester protecting groups and DCCI-promoted bond formation are to be shown.

Concept Introduction:

Direct reaction between two amino acids results in a mixture of four dipeptides.

Synthesis of a particular dipeptide as the sole product requires protecting the amine group of the amino acid that forms the N-terminus and the carboxyl group of the amino acid that forms the C-terminus of the peptide.

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