Chapter 26, Problem 48DSP

Interpretation Introduction

Interpretation:

The reaction conditions appropriate for the step 1 in the given reaction are to be determined on the basis of the information given.

Concept introduction:

The hydrogen atom attached to the alpha carbon atom of carbonyl compounds is acidic.

It can be abstracted by a base to generate an enolate ion.

The enolate ion can act as a nucleophile and react with alkyl halides via ${\text{S}}_{\text{N}}\text{2}$ type of reaction.