Chapter 26.10, Problem 2QQ

Interpretation Introduction

Interpretation: To identify the B vitamin involved in the oxidizing agent ${\text{NAD}}^{+}$ required for oxidative deamination reaction.

Concept introduction: Coenzymes are non-protein organic compounds that are used along with the enzymes and help to carry forward the reaction. Coenzymes cannot perform on their own alone. Nicotinamide adenine dinucleotide $\left({\text{NAD}}^{+}\right)$ is an example of a coenzyme.

Nicotinamide adenine dinucleotide $\left({\text{NAD}}^{+}\right)$ is employed in various metabolic reactions. It also acts as an oxidizing agent in various reactions like oxidation of secondary alcohol into a ketone. Nicotinamide adenine dinucleotide $\left({\text{NAD}}^{+}\right)$ exists in two forms. The structure of ${\text{NAD}}^{+}$ is:

Here, $\text{R}=\text{Ribose-ADP}$.

A biochemical reaction in which an $\text{α-amino}$ acid is converted into $\text{α-keto}$ acid along with the release of an ammonium ion is known as oxidative deamination reaction.