To determine the five nonessential amino acids that can be biosynthesized using citric acid cycle intermediates. Concept introduction: Essential amino acids are those amino acids which cannot be synthesized by the body via biosynthesis and thus must be taken from the outside in form of dietary protein to meet the body’s need. Those amino acids which can be synthesized by biosynthesis within the liver are termed as nonessential amino acids. The starting materials required for the biosynthesis of 10 nonessential amino acids within the human body are 3-phosphoglycerate , pyruvate, oxaloacetate, α-ketoglutarate and phenylalanine.

Question

For each reaction below, decide if the first stable organic product that forms in solution will create a new CC bond, and check the appropriate box. Next, for each reaction to which you answered "Yes" to in the table, draw this product in the drawing area below. Note for advanced students: for this problem, don't worry if you think this product will continue to react under the current conditions - just focus on the first stable product you expect to form in solution. དྲ。 ✗MgBr ? O CI Will the first product that forms in this reaction create a new C-C bond? Yes No • ? Will the first product that forms in this reaction create a new CC bond? Yes No × : ☐ X

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Question

Chapter 26, Problem 26.90EP

Interpretation Introduction

Interpretation: To determine the five nonessential amino acids that can be biosynthesized using citric acid cycle intermediates.

Concept introduction: Essential amino acids are those amino acids which cannot be synthesized by the body via biosynthesis and thus must be taken from the outside in form of dietary protein to meet the body’s need. Those amino acids which can be synthesized by biosynthesis within the liver are termed as nonessential amino acids.

The starting materials required for the biosynthesis of 10 nonessential amino acids within the human body are 3-phosphoglycerate, pyruvate, oxaloacetate, α-ketoglutarate and phenylalanine.

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