To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin in whose production “ring-opening” occurs. Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is: The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

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Answer 1

Question

Chapter 26, Problem 26.102EP

(a)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin in whose production “ring-opening” occurs.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(b)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin in whose production a carbon-carbon double bond is changed to a carbon-carbon single bond.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(c)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin that is rendered more water soluble by use of a glucose derivative.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

The structure of the heme group is:

(d)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin which is bile pigment and has a yellowish color.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Bile pigments are the colored degradation product of tetrapyrrole carbon arrangement of heme portion of hemoglobin. These are excreted in bile and give characteristic color to urine and feces.

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Answer 2

Question

Chapter 26, Problem 26.102EP

(a)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin in whose production “ring-opening” occurs.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(b)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin in whose production a carbon-carbon double bond is changed to a carbon-carbon single bond.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(c)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin that is rendered more water soluble by use of a glucose derivative.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

The structure of the heme group is:

(d)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin which is bile pigment and has a yellowish color.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Bile pigments are the colored degradation product of tetrapyrrole carbon arrangement of heme portion of hemoglobin. These are excreted in bile and give characteristic color to urine and feces.

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Answer 3

Question

Chapter 26, Problem 26.102EP

(a)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin in whose production “ring-opening” occurs.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(b)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin in whose production a carbon-carbon double bond is changed to a carbon-carbon single bond.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(c)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin that is rendered more water soluble by use of a glucose derivative.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

The structure of the heme group is:

(d)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin which is bile pigment and has a yellowish color.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Bile pigments are the colored degradation product of tetrapyrrole carbon arrangement of heme portion of hemoglobin. These are excreted in bile and give characteristic color to urine and feces.

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Answer 4

Question

Chapter 26, Problem 26.102EP

(a)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin in whose production “ring-opening” occurs.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(b)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin in whose production a carbon-carbon double bond is changed to a carbon-carbon single bond.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(c)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin that is rendered more water soluble by use of a glucose derivative.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

The structure of the heme group is:

(d)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin which is bile pigment and has a yellowish color.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Bile pigments are the colored degradation product of tetrapyrrole carbon arrangement of heme portion of hemoglobin. These are excreted in bile and give characteristic color to urine and feces.

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Check out a sample textbook solution

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Answer 5

Chapter 26, Problem 26.102EP

(a)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin in whose production “ring-opening” occurs.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(b)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin in whose production a carbon-carbon double bond is changed to a carbon-carbon single bond.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(c)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin that is rendered more water soluble by use of a glucose derivative.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

The structure of the heme group is:

(d)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin which is bile pigment and has a yellowish color.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Bile pigments are the colored degradation product of tetrapyrrole carbon arrangement of heme portion of hemoglobin. These are excreted in bile and give characteristic color to urine and feces.

Answer 6

Chapter 26, Problem 26.102EP

(a)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin in whose production “ring-opening” occurs.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Answer 7

Chapter 26, Problem 26.102EP

(a)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin in whose production “ring-opening” occurs.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Answer 8

(b)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin in whose production a carbon-carbon double bond is changed to a carbon-carbon single bond.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Answer 9

(b)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin in whose production a carbon-carbon double bond is changed to a carbon-carbon single bond.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Answer 10

(c)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin that is rendered more water soluble by use of a glucose derivative.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

The structure of the heme group is:

Answer 11

(c)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin that is rendered more water soluble by use of a glucose derivative.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

The structure of the heme group is:

Answer 12

(d)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin which is bile pigment and has a yellowish color.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Bile pigments are the colored degradation product of tetrapyrrole carbon arrangement of heme portion of hemoglobin. These are excreted in bile and give characteristic color to urine and feces.

Answer 13

(d)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin which is bile pigment and has a yellowish color.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Bile pigments are the colored degradation product of tetrapyrrole carbon arrangement of heme portion of hemoglobin. These are excreted in bile and give characteristic color to urine and feces.

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Answer 17

Ch. 26.1 - Which of the following statements about dietary...Ch. 26.1 - Dietary protein materials as they leave the...Ch. 26.1 - The inactive form of pepsin is converted to its...Ch. 26.1 - Which of the following is not a proteolytic...Ch. 26.2 - The dominant use for the amino acids of the amino...Ch. 26.2 - The most abundant amino acid in the amino acid...Ch. 26.2 - Prob. 3QQ Ch. 26.3 - Prob. 1QQ Ch. 26.3 - Prob. 2QQ Ch. 26.3 - The net effect of transamination is to collect the...

Solution Summary: The author explains the structure of the heme group, which contains 4 pyrrole groups bonded together and an iron atom in the center.

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