Becker's World of the Cell (9th Edition)
Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
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Chapter 26, Problem 26.8PS

QUANTITATIVE Cancer Screening. The annual incidence of colon cancer in the United States is about 55 cases per 100,000. Because colon cancer often causes bleeding, doctors sometimes use a screening procedure called the fecal occult blood test (FOBT) to look for tiny amounts of blood in the feces. One form of this test has a specificity of about 98%, which means that when it indicates the presence of blood in the feces, the result is an error (that is, cancer is not present) only 2% of the time. Although this may seem like excellent specificity, a 2% “false positive” rate makes this test almost useless as a tool for colon cancer screening. Why?

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