Becker's World of the Cell (9th Edition)
Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
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Chapter 26, Problem 1Q

Monoclonal antibodies directed against the CD20 antigen are used to treat certain forms of lymphoma. However, the CD20 antigen is present on both mature normal and malignant lymphocytes, and treatment with the antibody therefore kills normal cells as well as cancer cells. Why do you think this antibody still turns out to be an effective treatment for lymphoma?

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Plekhg5 functions in bottle cell formation, and Shroom3 functions in neural plate closure, yet the phenotype of injecting mRNA of each into the animal pole of a fertilized egg is very similar. What is the phenotype, and why is the phenotype so similar? Is the phenotype going to be that there is a disruption of the formation of the neural tube for both of these because bottle cell formation is necessary for the neural plate to fold in forming the neural tube and Shroom3 is further needed to close the neural plate? So since both Plekhg5 and Shroom3 are used in forming the neural tube, injecting the mRNA will just lead to neural tube deformity?
What are some medical issues or health trends that may have a direct link to the idea of keeping fat out of diets?
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