Chapter 26, Problem 26.4CC

Summary Introduction

To determine: The similarities and differences for the types of mutations that lead to cancer in the tumor suppressor genes and proto-oncogenes.

Introduction: Cancer is caused due to the failure of the regulation of the cell cycle. The cell cycle has many stages and each stage have been provided with a number of the check points which prevents the cell to move to the next phase of the cycle. The failure of these cycles is attributed to the genes which are altered by the mutagens and now are producing the abnormal protein. When the protein associated with the regulation of the cell cycle is abnormal then control on the cell cycle will be lost and there will be an uncontrolled increase in the number of the cell.