EBK ORGANIC CHEMISTRY STUDY GUIDE AND S
EBK ORGANIC CHEMISTRY STUDY GUIDE AND S
6th Edition
ISBN: 9781319385415
Author: PARISE
Publisher: VST
Question
Book Icon
Chapter 25, Problem 25.9P
Interpretation Introduction

(a)

Interpretation:

The given reaction is to be completed.

Concept Introduction:

Thioesters react with nucleophiles in acyl substitution reactions via addition-elimination mechanism. If the nucleophile is an amine, then the product formed in these reactions is an amide.

Interpretation Introduction

(b)

Interpretation:

It is to be explained why the reaction of the thioester and the amine is thermodynamically favorable under neutral conditions but the reaction is not observed in presence of an acid.

Concept introduction:

Blurred answer
Students have asked these similar questions
How would you prepare 1 liter of a 50 mM Phosphate buffer at pH 7.5 beginning with K3PO4 and 1 M HCl or 1 M NaOH? Please help and show calculations. Thank you
Draw the four most importantcontributing structures of the cation intermediate thatforms in the electrophilic chlorination of phenol,(C6H5OH) to form p-chlorophenol. Put a circle aroundthe best one. Can you please each step and also how you would approach a similar problem. Thank you!
A 100mM lactic acid/lactate buffer was found to have a lactate to lactic acid ratio of 2 and a pH of 4.2. What is the pKa of lactic acid? Can you please help show the calculations?
Knowledge Booster
Background pattern image
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
  • Text book image
    Organic Chemistry
    Chemistry
    ISBN:9781305080485
    Author:John E. McMurry
    Publisher:Cengage Learning
Text book image
Organic Chemistry
Chemistry
ISBN:9781305080485
Author:John E. McMurry
Publisher:Cengage Learning