The key catalytic features in the active sites of the enzymes U D P - g l u c u r o n y l t r a n s f e r a s e s in the conversion of conjugated alcohols into glucuronides, is to be described. Concept Introduction: The active site of the enzyme should contain a glutamate or aspartate residue to remove a proton from phenol. The negative charges on phosphates are stabilized by magnesium or calcium ions.

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Chapter 25, Problem 25.33AP

Interpretation Introduction

Interpretation:

The key catalytic features in the active sites of the enzymes UDP-glucuronyl transferases in the conversion of conjugated alcohols into glucuronides, is to be described.

Concept Introduction:

The active site of the enzyme should contain a glutamate or aspartate residue to remove a proton from phenol. The negative charges on phosphates are stabilized by magnesium or calcium ions.

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