
Concept explainers
(a)
Interpretation:
The
Concept introduction:
Ketone bodies are water soluble molecules which are synthesized from acetyl CoA through the process of ketogenesis. Ketogenesis occurs in the mitochondria of the liver cells. The initial reactants are the molecules of acetyl CoA which are produced by the β-oxidation of fatty acid molecules. Ketone bodies are generally produced when the amount of acetyl CoA in the body is much larger than the amount of oxaloacetate. This happens due to the carbohydrate-lipid imbalance in the body caused by much smaller intake of food rich in carbohydrates, or inefficient processing of glucose by the body.
(b)
Interpretation:
The ketone body/bodies with a hydroxyl group in its structure has to be determined.
Concept introduction:
Ketone bodies are water soluble molecules which are synthesized from acetyl CoA through the process of ketogenesis. Ketogenesis occurs in the mitochondria of the liver cells. The initial reactants are the molecules of acetyl CoA which are produced by the β-oxidation of fatty acid molecules. Ketone bodies are generally produced when the amount of acetyl CoA in the body is much larger than the amount of oxaloacetate. This happens due to the carbohydrate-lipid imbalance in the body caused by much smaller intake of food rich in carbohydrates, or inefficient processing of glucose by the body.
(c)
Interpretation:
The ketone body produced in step 3 of ketogenesis has to be identified.
Concept introduction:
Ketone bodies are water soluble molecules which are synthesized from acetyl CoA through the process of ketogenesis. Ketogenesis occurs in the mitochondria of the liver cells. The initial reactants are the molecules of acetyl CoA which are produced by the β-oxidation of fatty acid molecules. Ketone bodies are generally produced when the amount of acetyl CoA in the body is much larger than the amount of oxaloacetate. This happens due to the carbohydrate-lipid imbalance in the body caused by much smaller intake of food rich in carbohydrates, or inefficient processing of glucose by the body.
(d)
Interpretation:
The ketone body produced from the decomposition of acetoacetate is to be determined.
Concept introduction:
Ketone bodies are water soluble molecules which are synthesized from acetyl CoA through the process of ketogenesis. Ketogenesis occurs in the mitochondria of the liver cells. The initial reactants are the molecules of acetyl CoA which are produced by the β-oxidation of fatty acid molecules. Ketone bodies are generally produced when the amount of acetyl CoA in the body is much larger than the amount of oxaloacetate. This happens due to the carbohydrate-lipid imbalance in the body caused by much smaller intake of food rich in carbohydrates, or inefficient processing of glucose by the body.

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Chapter 25 Solutions
General, Organic, and Biological Chemistry Seventh Edition
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