GENERAL,ORGANIC,+BIO.CHEM.-MINDTAP
7th Edition
ISBN: 9781305866966
Author: STOKER
Publisher: CENGAGE L
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 25, Problem 25.45EP
Interpretation Introduction
Interpretation:
The nature of the extra step needed for the degradation of cis-3-hexanoic acid, a
Concept introduction:
The β-oxidation pathway is defined as a repetitive series of four biochemical reactions in which acyl CoA is degraded to acetyl CoA by the removal of two carbon atoms at a time. NADH and FADH2 are also produced in this pathway.
Unsaturated fatty acids are common components of dietary triacylglycerols. The oxidation process of unsaturated fatty acids through the β-oxidation pathway needed two additional enzymes besides those that are needed for the oxidation of saturated fatty acids.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
The purinosome contains enzymes that convert the serine hydroxymethylgroup to the formyl group of 10-formyltetrahydrofolate. Write a balancedequation for each reaction in this conversion.
Radioactive uracil can be used to label all of the pyrimidine residues inDNA. Using either names or structures, present pathways for the conversionof uracil to dTTP and to dCTP. For each reaction, show the involvement ofcofactors, and identify sites of allosteric regulation.
Similarly, hypoxanthine (HX) can be used to label purine residues. As given above, write reactions showing the conversion of hypoxanthine to dATP and dGTP.
In the pyrimidine degradative pathway, all pyrimidines undergo conversion
to uracil, which undergoes an NADPH-dependent reduction. Show plausible
reactions leading from cytidine, cytosine, and uridine to uracil, and write a
plausible structure for the product of uracil reduction (dihydrouracil).
Chapter 25 Solutions
GENERAL,ORGANIC,+BIO.CHEM.-MINDTAP
Ch. 25.1 - Which of the following statements about digestion...Ch. 25.1 - Prob. 2QQCh. 25.1 - The major function of bile released during...Ch. 25.1 - The two major products of triacylglycerol...Ch. 25.1 - Prob. 5QQCh. 25.2 - Hormone-sensitive lipase needed for...Ch. 25.2 - Prob. 2QQCh. 25.2 - Which of the following is not a product of...Ch. 25.3 - Prob. 1QQCh. 25.3 - What is the intermediate compound in the two-step...
Ch. 25.3 - Prob. 3QQCh. 25.4 - Prob. 1QQCh. 25.4 - Prob. 2QQCh. 25.4 - Prob. 3QQCh. 25.4 - Prob. 4QQCh. 25.4 - Prob. 5QQCh. 25.4 - Prob. 6QQCh. 25.5 - Prob. 1QQCh. 25.5 - Prob. 2QQCh. 25.5 - Prob. 3QQCh. 25.6 - Prob. 1QQCh. 25.6 - Prob. 2QQCh. 25.6 - Prob. 3QQCh. 25.6 - Prob. 4QQCh. 25.6 - Prob. 5QQCh. 25.6 - Prob. 6QQCh. 25.7 - Prob. 1QQCh. 25.7 - Prob. 2QQCh. 25.7 - Prob. 3QQCh. 25.7 - Prob. 4QQCh. 25.7 - The reducing agent needed in the process of...Ch. 25.7 - Prob. 6QQCh. 25.8 - Prob. 1QQCh. 25.8 - Prob. 2QQCh. 25.9 - Prob. 1QQCh. 25.9 - Prob. 2QQCh. 25.9 - Prob. 3QQCh. 25.9 - Prob. 4QQCh. 25.10 - Which of the following substances cannot be...Ch. 25.10 - Prob. 2QQCh. 25.10 - Which of the following processes occurs within the...Ch. 25.11 - Prob. 1QQCh. 25.11 - Prob. 2QQCh. 25.11 - Prob. 3QQCh. 25 - Indicate whether each of the following aspects of...Ch. 25 - Indicate whether each of the following aspects of...Ch. 25 - Indicate whether each of the following pairings of...Ch. 25 - Prob. 25.4EPCh. 25 - Indicate whether each of the following statements...Ch. 25 - Prob. 25.6EPCh. 25 - Prob. 25.7EPCh. 25 - What is a chylomicron?Ch. 25 - What are the products of the complete hydrolysis...Ch. 25 - What are the major products of the incomplete...Ch. 25 - Prob. 25.11EPCh. 25 - At what location are free fatty acids and...Ch. 25 - Prob. 25.13EPCh. 25 - Prob. 25.14EPCh. 25 - Prob. 25.15EPCh. 25 - Prob. 25.16EPCh. 25 - Prob. 25.17EPCh. 25 - Prob. 25.18EPCh. 25 - Prob. 25.19EPCh. 25 - Prob. 25.20EPCh. 25 - Prob. 25.21EPCh. 25 - Prob. 25.22EPCh. 25 - Prob. 25.23EPCh. 25 - Prob. 25.24EPCh. 25 - Prob. 25.25EPCh. 25 - Prob. 25.26EPCh. 25 - Prob. 25.27EPCh. 25 - Identify the oxidizing agent needed in Step 3 of a...Ch. 25 - Prob. 25.29EPCh. 25 - Prob. 25.30EPCh. 25 - Prob. 25.31EPCh. 25 - Prob. 25.32EPCh. 25 - Prob. 25.33EPCh. 25 - Prob. 25.34EPCh. 25 - Prob. 25.35EPCh. 25 - Prob. 25.36EPCh. 25 - Prob. 25.37EPCh. 25 - Prob. 25.38EPCh. 25 - Prob. 25.39EPCh. 25 - Prob. 25.40EPCh. 25 - Prob. 25.41EPCh. 25 - Prob. 25.42EPCh. 25 - How many turns of the -oxidation pathway would be...Ch. 25 - How many turns of the -oxidation pathway would be...Ch. 25 - Prob. 25.45EPCh. 25 - Prob. 25.46EPCh. 25 - Prob. 25.47EPCh. 25 - Prob. 25.48EPCh. 25 - Prob. 25.49EPCh. 25 - Explain why fatty acids cannot serve as fuel for...Ch. 25 - Prob. 25.51EPCh. 25 - Prob. 25.52EPCh. 25 - Prob. 25.53EPCh. 25 - Prob. 25.54EPCh. 25 - Prob. 25.55EPCh. 25 - Prob. 25.56EPCh. 25 - Prob. 25.57EPCh. 25 - Prob. 25.58EPCh. 25 - Prob. 25.59EPCh. 25 - Prob. 25.60EPCh. 25 - Prob. 25.61EPCh. 25 - Why does a deficiency of carbohydrates in the diet...Ch. 25 - Prob. 25.63EPCh. 25 - Prob. 25.64EPCh. 25 - Prob. 25.65EPCh. 25 - Prob. 25.66EPCh. 25 - Prob. 25.67EPCh. 25 - Prob. 25.68EPCh. 25 - Prob. 25.69EPCh. 25 - Prob. 25.70EPCh. 25 - Prob. 25.71EPCh. 25 - Prob. 25.72EPCh. 25 - Prob. 25.73EPCh. 25 - Prob. 25.74EPCh. 25 - Prob. 25.75EPCh. 25 - Severe ketosis situations produce acidosis....Ch. 25 - Prob. 25.77EPCh. 25 - Prob. 25.78EPCh. 25 - Prob. 25.79EPCh. 25 - Prob. 25.80EPCh. 25 - Prob. 25.81EPCh. 25 - Prob. 25.82EPCh. 25 - Prob. 25.83EPCh. 25 - Prob. 25.84EPCh. 25 - Prob. 25.85EPCh. 25 - Prob. 25.86EPCh. 25 - Prob. 25.87EPCh. 25 - Prob. 25.88EPCh. 25 - Prob. 25.89EPCh. 25 - Prob. 25.90EPCh. 25 - Prob. 25.91EPCh. 25 - Prob. 25.92EPCh. 25 - Prob. 25.93EPCh. 25 - Prob. 25.94EPCh. 25 - What role does molecular oxygen, O2, play in fatty...Ch. 25 - Prob. 25.96EPCh. 25 - Prob. 25.97EPCh. 25 - Prob. 25.98EPCh. 25 - Prob. 25.99EPCh. 25 - Prob. 25.100EPCh. 25 - Prob. 25.101EPCh. 25 - Prob. 25.102EPCh. 25 - Prob. 25.103EPCh. 25 - Prob. 25.104EPCh. 25 - Prob. 25.105EPCh. 25 - Prob. 25.106EPCh. 25 - Prob. 25.107EPCh. 25 - Prob. 25.108EPCh. 25 - Prob. 25.109EPCh. 25 - Prob. 25.110EPCh. 25 - Prob. 25.111EPCh. 25 - Prob. 25.112EPCh. 25 - Prob. 25.113EPCh. 25 - Prob. 25.114EP
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Similar questions
- Dihydrouracil and β-ureidopropionate (N-carbamoyl–β-alanine) are intermediates in the conversion of uracil to β-alanine. Provide the structures of the molecules in this pathway.arrow_forwardHistidine is frequently used as a general acid or base in enzyme catalysis. Considering the pKa value of the side chain, suggest a reason why is this so?arrow_forwardSome of the following four amino acids : alanine, arginine, histidine, aspartic acid would provide a side chain for acid-base catalysis at physiological pH (assume pK of each amino acid is equal to pK value for the free amino acid in solution). Explain for each amino acid how and why each would or would not provide the side chain residue to support acid-base catalysis at physiological pH.arrow_forward
- A reaction involved in the metabolism of sugars is the splitting of fructose-1,6-diphosphate to give glyceraldehyde-3- phosphate and dihydroxyacetone phosphate. In the living system, this retro-aldol is catalyzed by an enzyme called aldolase; however, it can also be catalyzed by a mild base. Propose a mechanism for the base-catalyzed reaction. CH,-0-P-0- CH,-0-P-0- C=0 C=0 CH,OH dihydroxyacetone phosphate HO-C-H aldolase or "OH H-C-OH H-C-OH H-C-OH CH,-0-P-0- CH2-0-P-0- fructose-1,6-diphosphate glyceraldehyde-3-phosphatearrow_forwardA certain plant storage protein, after being isolated, was digested using both 8N H2SO4 and conc. Ba(OH)2. The resulting hydrolysates were then analyzed for amino acid composition using paper chromatography with EtOH-NH3-H2O (80:10:10) as the solvent system and ninhydrin as the visualizing agent. Name the amino acids found in the acid hydrolysate labelled 1-5.arrow_forwardOne can identify phenylketonurics and PKU carriers (heterozygotes) by means of a phenylalanine tolerance test. One injects a large dose of pheny- lalanine into the bloodstream and measures its clearance from the blood by measuring serum phenylalanine levels at regular intervals. Sketch curves showing relative blood phenylalanine concentration versus time that you would expect to be displayed by (a) a PKU patient, (b) a heterozygote, and (c) a normal individual. What kind of tolerance test could you devise to distinguish between PKU resulting from either phenylalanine hydroxylase deficiency or dihydropteridine reductase deficiency?arrow_forward
- Lysine degradation requires removal of two amino groups. Removal of itsε-amino group gives a-aminoadipic semialdehyde. This product is thendegraded to acetoacetate by the same chemical strategy used to degrade thebranched-chain amino acids. Draw the proposed intermediates in this pathway (Hint: see Figure 18.14).arrow_forwardDraw the structure of the PTH derivative product you would obtain by Edman degradation of the following peptides: (a) I-L-P-F (b) D-T-S-G-Aarrow_forwardThere are two competing processes for the manufacture of lactic acid, chemical and biochemical syntheses. The chemical synthesis involves the hydrocyanation of acetaldehyde, while the biochemical synthesis involves the fermentation of sugars or starch. Discuss the TWO advantages and THREE disadvantages of synthesising lactic acid via the biochemical route.arrow_forward
- If thymine nucleotides are degraded by the same enzymes as those catabolizing uridine nucleotides, give the structure of the thymine metabolite that corresponds to B-ureidopropionate.arrow_forwardThere is a cysteine protease, which uses a similar chemical mechanism to chymotrypsin except for using cysteine instead of serine during catalysis. Please draw the stepwise chemical mechanism for the cysteine protease.arrow_forwardExplain the basis for the following statement. For efficient conver- sion of galactose to glucose-1-phosphate, UDP-glucose need be present in catalytic amounts only.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education