To indicate whether the statement “pyruvate is converted to lactate in the skeletal muscle” relating to the Cori cycle is true or false. Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle. The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

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Answer 1

Question

Chapter 24, Problem 24.80EP

(a)

Interpretation Introduction

Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the skeletal muscle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

(b)

Interpretation Introduction

Interpretation: To indicate whether the statement “glucose from the liver travels to skeletal muscle as part of the cycle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

(c)

Interpretation Introduction

Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the liver” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

(d)

Interpretation Introduction

Interpretation: To indicate whether the statement “both lactate and pyruvate are present in skeletal muscle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

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Answer 2

Question

Chapter 24, Problem 24.80EP

(a)

Interpretation Introduction

Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the skeletal muscle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

(b)

Interpretation Introduction

Interpretation: To indicate whether the statement “glucose from the liver travels to skeletal muscle as part of the cycle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

(c)

Interpretation Introduction

Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the liver” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

(d)

Interpretation Introduction

Interpretation: To indicate whether the statement “both lactate and pyruvate are present in skeletal muscle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

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Answer 3

Question

Chapter 24, Problem 24.80EP

(a)

Interpretation Introduction

Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the skeletal muscle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

(b)

Interpretation Introduction

Interpretation: To indicate whether the statement “glucose from the liver travels to skeletal muscle as part of the cycle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

(c)

Interpretation Introduction

Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the liver” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

(d)

Interpretation Introduction

Interpretation: To indicate whether the statement “both lactate and pyruvate are present in skeletal muscle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

Expert Solution & Answer

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Answer 4

Question

Chapter 24, Problem 24.80EP

(a)

Interpretation Introduction

Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the skeletal muscle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

(b)

Interpretation Introduction

Interpretation: To indicate whether the statement “glucose from the liver travels to skeletal muscle as part of the cycle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

(c)

Interpretation Introduction

Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the liver” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

(d)

Interpretation Introduction

Interpretation: To indicate whether the statement “both lactate and pyruvate are present in skeletal muscle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

Expert Solution & Answer

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Answer 5

Chapter 24, Problem 24.80EP

(a)

Interpretation Introduction

Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the skeletal muscle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

(b)

Interpretation Introduction

Interpretation: To indicate whether the statement “glucose from the liver travels to skeletal muscle as part of the cycle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

(c)

Interpretation Introduction

Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the liver” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

(d)

Interpretation Introduction

Interpretation: To indicate whether the statement “both lactate and pyruvate are present in skeletal muscle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

Answer 6

Chapter 24, Problem 24.80EP

(a)

Interpretation Introduction

Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the skeletal muscle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

Answer 7

Chapter 24, Problem 24.80EP

(a)

Interpretation Introduction

Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the skeletal muscle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

Answer 8

(b)

Interpretation Introduction

Interpretation: To indicate whether the statement “glucose from the liver travels to skeletal muscle as part of the cycle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

Answer 9

(b)

Interpretation Introduction

Interpretation: To indicate whether the statement “glucose from the liver travels to skeletal muscle as part of the cycle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

Answer 10

(c)

Interpretation Introduction

Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the liver” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

Answer 11

(c)

Interpretation Introduction

Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the liver” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

Answer 12

(d)

Interpretation Introduction

Interpretation: To indicate whether the statement “both lactate and pyruvate are present in skeletal muscle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

Answer 13

(d)

Interpretation Introduction

Interpretation: To indicate whether the statement “both lactate and pyruvate are present in skeletal muscle” relating to the Cori cycle is true or false.

Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.

The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

Answer 14

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Answer 15

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Answer 17

Ch. 24.1 - The primary site within the human body where...Ch. 24.1 - What is the first site within the human body where...Ch. 24.1 - What effect does gastric juice in the stomach have...Ch. 24.1 - Prob. 4QQ Ch. 24.1 - Which of the following substances is needed for...Ch. 24.2 - Prob. 1QQ Ch. 24.2 - Prob. 2QQ Ch. 24.2 - Prob. 3QQ Ch. 24.2 - Prob. 4QQ Ch. 24.2 - Prob. 5QQ

Solution Summary: The author explains how pyruvate is converted to lactate in the skeletal muscle by glycolysis metabolic pathway, anaerobic reactions, and the Cori cycle.

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Chapter 24 Solutions