
Concept explainers
(a)
Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the skeletal muscle” relating to the Cori cycle is true or false.
Concept introduction: Glucose is converted to pyruvate by glycolysis
The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.
(b)
Interpretation: To indicate whether the statement “glucose from the liver travels to skeletal muscle as part of the cycle” relating to the Cori cycle is true or false.
Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.
The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.
(c)
Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the liver” relating to the Cori cycle is true or false.
Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.
The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.
(d)
Interpretation: To indicate whether the statement “both lactate and pyruvate are present in skeletal muscle” relating to the Cori cycle is true or false.
Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.
The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.

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Chapter 24 Solutions
GENERAL,ORGANIC,+BIO.CHEM.-MINDTAP
- Indicate the products obtained by mixing 2,2-dimethylpropanal with acetaldehyde and sodium ethoxide in ethanol.arrow_forwardSynthesize 2-Ethyl-3-methyloxirane from dimethyl(propyl)sulfonium iodide using the necessary organic or inorganic reagents. Draw the structures of the compounds.arrow_forwardSynthesize 2-Hydroxy-2-phenylacetonitrile from phenylmethanol using the necessary organic or inorganic reagents. Draw the structures of the compounds.arrow_forward
- Synthesize N-Methylcyclohexylamine from cyclohexanol using the necessary organic or inorganic reagents. Draw the structures of the compounds.arrow_forwardSynthesize N-Methylcyclohexylamine from cyclohexanol using the necessary organic or inorganic reagents. Draw the structures of the compounds.arrow_forwardIf possible, please provide the formula of the compound 3,3-dimethylbut-2-enal.arrow_forward
- Synthesize 1,4-dibromobenzene from acetanilide (N-phenylacetamide) using the necessary organic or inorganic reagents. Draw the structures of the compounds.arrow_forwardIndicate the products obtained by mixing (3-oxo-3-phenylpropyl)triphenylphosphonium bromide with sodium hydride.arrow_forwardWe mix N-ethyl-2-hexanamine with excess methyl iodide and followed by heating with aqueous Ag2O. Indicate the major products obtained.arrow_forward
- Indicate the products obtained by mixing acetophenone with iodine and NaOH.arrow_forwardIndicate the products obtained by mixing 2-Propanone and ethyllithium and performing a subsequent acid hydrolysis.arrow_forwardIndicate the products obtained if (E)-2-butenal and 3-oxo-butanenitrile are mixed with sodium ethoxide in ethanol.arrow_forward
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