Organic Chemistry
Organic Chemistry
8th Edition
ISBN: 9781305580350
Author: William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher: Cengage Learning
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Chapter 24, Problem 24.31P
Interpretation Introduction

Interpretation:

The possible reactants that would be placed in boxes in the sequence of Sonogashira coupling has to be given.

Concept Introduction:

Sonogashira coupling starts with a terminal alkyne with CuI and triethylamine to create a Cu- alkyne complex. This undergoes reaction with vinyl or aryl iodides.

This coupling is used to create diaryl alkynes, aryl alkenyl alkynes, or dialkenyl alkynes.

Organic Chemistry, Chapter 24, Problem 24.31P

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