(a) Interpretation: The starting materials needed to prepare the given drug using reductive amination are to be determined. Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

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Answer 1

Question

Chapter 23.6, Problem 14P

Interpretation Introduction

(a)

Interpretation: The starting materials needed to prepare the given drug using reductive amination are to be determined.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Interpretation Introduction

(b)

Interpretation: The starting materials needed to prepare the given drug using reductive amination are to be determined.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

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(f) SO: Best Lewis Structure 3 e group geometry:_ shape/molecular geometry:, (g) CF2CF2 Best Lewis Structure polarity: e group arrangement:_ shape/molecular geometry: (h) (NH4)2SO4 Best Lewis Structure polarity: e group arrangement: shape/molecular geometry: polarity: Sketch (with angles): Sketch (with angles): Sketch (with angles):

1. Problem Set 3b Chem 141 For each of the following compounds draw the BEST Lewis Structure then sketch the molecule (showing bond angles). Identify (i) electron group geometry (ii) shape around EACH central atom (iii) whether the molecule is polar or non-polar (iv) (a) SeF4 Best Lewis Structure e group arrangement:_ shape/molecular geometry: polarity: (b) AsOBr3 Best Lewis Structure e group arrangement:_ shape/molecular geometry: polarity: Sketch (with angles): Sketch (with angles):

(c) SOCI Best Lewis Structure 2 e group arrangement: shape/molecular geometry:_ (d) PCls Best Lewis Structure polarity: e group geometry:_ shape/molecular geometry:_ (e) Ba(BrO2): Best Lewis Structure polarity: e group arrangement: shape/molecular geometry: polarity: Sketch (with angles): Sketch (with angles): Sketch (with angles):

Answer 2

Question

Chapter 23.6, Problem 14P

Interpretation Introduction

(a)

Interpretation: The starting materials needed to prepare the given drug using reductive amination are to be determined.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Interpretation Introduction

(b)

Interpretation: The starting materials needed to prepare the given drug using reductive amination are to be determined.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

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Answer 3

Question

Chapter 23.6, Problem 14P

Interpretation Introduction

(a)

Interpretation: The starting materials needed to prepare the given drug using reductive amination are to be determined.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Interpretation Introduction

(b)

Interpretation: The starting materials needed to prepare the given drug using reductive amination are to be determined.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

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Answer 4

Question

Chapter 23.6, Problem 14P

Interpretation Introduction

(a)

Interpretation: The starting materials needed to prepare the given drug using reductive amination are to be determined.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Interpretation Introduction

(b)

Interpretation: The starting materials needed to prepare the given drug using reductive amination are to be determined.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

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Answer 5

Chapter 23.6, Problem 14P

Interpretation Introduction

(a)

Interpretation: The starting materials needed to prepare the given drug using reductive amination are to be determined.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Interpretation Introduction

(b)

Interpretation: The starting materials needed to prepare the given drug using reductive amination are to be determined.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Answer 6

Chapter 23.6, Problem 14P

Interpretation Introduction

(a)

Interpretation: The starting materials needed to prepare the given drug using reductive amination are to be determined.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Answer 7

Chapter 23.6, Problem 14P

Interpretation Introduction

(a)

Interpretation: The starting materials needed to prepare the given drug using reductive amination are to be determined.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Answer 8

Interpretation Introduction

(b)

Interpretation: The starting materials needed to prepare the given drug using reductive amination are to be determined.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Answer 9

Interpretation Introduction

(b)

Interpretation: The starting materials needed to prepare the given drug using reductive amination are to be determined.

Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.

Answer 10

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Answer 11

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Answer 12

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Answer 13

Ch. 23.2 - Prob. 1P Ch. 23.3 - Prob. 2P Ch. 23.3 - Prob. 3P Ch. 23.4 - Prob. 4P Ch. 23.6 - Prob. 7P Ch. 23.6 - Prob. 8P Ch. 23.6 - Prob. 9P Ch. 23.6 - Prob. 10P Ch. 23.6 - Prob. 11P Ch. 23.6 - Prob. 12P

Solution Summary: The author explains that the starting materials needed to prepare the given drug using reductive amination are shown in Figure 2.

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