
(a)
Interpretation:
The product obtained in the reaction of isopropylamine with dilute
Concept introduction:

Answer to Problem 23.46AP
The product
Explanation of Solution
The reaction of amines with dilute
Figure 1
The product obtained in the reaction of isopropylamine with dilute
(b)
Interpretation:
The product obtained in the reaction of isopropylamine with a dilute
Concept introduction:
Amines are the organic compounds that are formed by replacement of hydrogen from ammonia with a substituent. It may be alkyl or aryl group. Amines are basic in nature because the nitrogen can donate its lone pairs and it also has the ability to accept the proton in water.

Answer to Problem 23.46AP
The reaction does not form any product. The reaction is shown below.
Explanation of Solution
When isopropylamine reacts with a dilute
Figure 2
No product is obtained in the reaction of isopropylamine with a dilute
(c)
Interpretation:
The product obtained in the reaction of isopropylamine with butyllithium in
Concept introduction:
Amines are the organic compounds that are formed by replacement of hydrogen from ammonia with a substituent. It may be alkyl or aryl group. Amines are basic in nature because the nitrogen can donate its lone pairs and it also has the ability to accept the proton in water.

Answer to Problem 23.46AP
The product lithium isopropylamide is obtained in the reaction of isopropylamine with butyllithium in
Explanation of Solution
The organolithium base butyllithium in
Figure 3
The product obtained in the reaction of isopropylamine with butyllithium in
(d)
Interpretation:
The product obtained in the reaction of isopropylamine with acetyl chloride and pyridine is to be stated.
Concept introduction:
Amines are the organic compounds that are formed by replacement of hydrogen from ammonia with a substituent. It may be alkyl or aryl group. Amines are basic in nature because the nitrogen can donate its lone pairs and it also has the ability to accept the proton in water.

Answer to Problem 23.46AP
The product,
Explanation of Solution
The acid chloride is a very reactive compound. When it reacts with amines it forms amides. The reaction of isopropylamine with acetyl chloride in pyridine results in the formation of
Figure 4
The product obtained in the reaction of isopropylamine with acetyl chloride and pyridine is
(e)
Interpretation:
The product obtained in the reaction of isopropylamine with
Concept introduction:
Amines are the organic compounds that are formed by replacement of hydrogen from ammonia with a substituent. It may be alkyl or aryl group. The formation of diazonium salt from

Answer to Problem 23.46AP
The product,
Explanation of Solution
The reaction is an example of a diazotization reaction. When isopropylamine reacts with
Figure 5
The product that obtained in the reaction of isopropylamine with
(f)
Interpretation:
The product obtained in the reaction of isopropylamine with acetone and
Concept introduction:
Amines are the organic compounds that are formed by replacement of hydrogen from ammonia with a substituent. It may be alkyl or aryl group. Amines are basic in nature because the nitrogen can donate its lone pairs and it also has the ability to accept the proton in water.

Answer to Problem 23.46AP
Explanation of Solution
When acetone reacts with isopropylamine, it forms enamine, with double bonds. It is then hydrogenated by
Figure 6
The product obtained in the reaction of isopropylamine with acetone and
(g)
Interpretation:
The product obtained in the reaction of isopropylamine with excess
Concept introduction:
Amines are the organic compounds that are formed by replacement of hydrogen from ammonia with a substituent. It may be alkyl or aryl group. Hofmann elimination reaction occurs as an anti-elimination reaction. In this reaction, the starting material is quaternary ammonium hydroxide. When quaternary ammonium hydroxide is heated,

Answer to Problem 23.46AP
The product,
Explanation of Solution
Hofmann elimination reaction occurs as an anti-elimination reaction. In this reaction, the starting material is isopropylamine. When it reacts with an excess of
Figure 7
The product obtained in the reaction of isopropylamine with excess
(h)
Interpretation:
The product obtained in the reaction of isopropylamine with benzoic acid at
Concept introduction:
Amines are the organic compounds that are formed by replacement of hydrogen from ammonia with a substituent. It may be alkyl or aryl group. Amines are basic in nature because the nitrogen can donate its lone pairs and it also has the ability to accept the proton in water.

Answer to Problem 23.46AP
The product
Explanation of Solution
In this reaction, benzoic acid is a reactive compound. When it reacts with amine it results in the formation of an amide. This reaction is similar to the conversion of carboxylic acid to amides. The reaction is shown below.
Figure 8
The product obtained in the reaction of isopropylamine with benzoic acid at
(i)
Interpretation:
The product obtained in the reaction of isopropylamine with formaldehyde,
Concept introduction:
Amines are the organic compounds that are formed by replacement of hydrogen from ammonia with a substituent. It may be alkyl or aryl group. Amines are basic in nature because the nitrogen can donate its lone pairs and it also has the ability to accept the proton in water.

Answer to Problem 23.46AP
The product
Explanation of Solution
This reaction is an example of a reductive amination reaction. Reductive amination reaction is the conversion of the carbonyl group to the amine or it converts one amine to newer amine. In this reaction, when isopropylamine reacts formaldehyde,
Figure 9
The product that obtained in the reaction of isopropylamine with formaldehyde,
(j)
Interpretation:
The product obtained in the reaction of isopropylamine with
Concept introduction:
Amines are the organic compounds that are formed by replacement of hydrogen from ammonia with a substituent. It may be alkyl or aryl group. Amines are basic in nature because the nitrogen can donate its lone pairs and it also has the ability to accept the proton in water.

Answer to Problem 23.46AP
The product
Explanation of Solution
This reaction is an example of a Buchwald-Hartwig reaction. Buchwald Hartwig reaction is used for
Figure 10
The product obtained in the reaction of isopropylamine with
(k)
Interpretation:
The product obtained in the reaction of isopropylamine with a product of part (g) +
Concept introduction:
Amines are the organic compounds that are formed by replacement of hydrogen from ammonia with a substituent. It may be alkyl or aryl group. Hofmann elimination reaction occurs as an anti-elimination reaction. In this reaction, the starting material is quaternary ammonium hydroxide. When quaternary ammonium hydroxide is heated,

Answer to Problem 23.46AP
The product
Explanation of Solution
When isopropylamine undergoes Hofmann elimination reaction with a product of part (g)
Figure 11
The product obtained in the reaction of isopropylamine with a product of part (g)
(l)
Interpretation:
The product obtained in the reaction of isopropylamine with a product of part (d) with
Concept introduction:
Amines are the organic compounds that are formed by replacement of hydrogen from ammonia with a substituent. It may be alkyl or aryl group. Amines are basic in nature because the nitrogen can donate its lone pairs and it also has the ability to accept the proton in water.

Answer to Problem 23.46AP
The product,
Explanation of Solution
When
Figure 12
The product obtained in the reaction of isopropylamine with a product of part (d) with
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Chapter 23 Solutions
Organic Chemistry, Ebook And Single-course Homework Access
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- Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage Learning
