Chapter 23, Problem 23.37P

Interpretation Introduction

(a)

Interpretation:

The compound, $N\text{-}\left(sec\text{-butyl}\right)\text{-}N\text{-ethylaniline}$ from chlorobenzene is to be synthesized.

Concept introduction:

Butchwald-Hatwig amination is the reaction in which aryl halides are directly aminated in the presence of a base and a catalyst to form aryl amines. The palladium catalyst is used in this reaction is ${\text{PdL}}_{\text{2}}$, where, L stands for ligand. The mechanism of this reaction includes oxidative addition and reductive elimination.

Interpretation Introduction

(b)

Interpretation:

The compound, $\text{4-}\left(\text{4-}tert\text{-butylphenyl}\right)\text{morpholine}$ from phenol is to be synthesized.

Concept introduction:

Butchwald-Hatwig amination is the reaction in which aryl halides are directly aminated in the presence of a base and a catalyst to form aryl amines. The catalyst used in this reaction is of the form ${\text{PdL}}_{\text{2}}$, where, L stands for ligand. The mechanism of this reaction includes oxidative addition and reductive elimination.

Interpretation Introduction

(c)

Interpretation:

The compound, $\text{phenyl}\left(\text{4-}\left(\text{phenylamino}\right)\text{phenyl}\right)\text{methane}$ from chlorobenzene is to be synthesized.

Concept introduction:

Butchwald-Hatwig amination is the reaction in which aryl halides are directly aminated in the presence of a base and a catalyst to form aryl amines. The catalyst used in this reaction is of the form ${\text{PdL}}_{\text{2}}$, where, L stands for ligand. The mechanism of this reaction includes oxidative addition and reductive elimination. ${\text{AlCl}}_{\text{3}}$