Chapter 23, Problem 18P

Interpretation Introduction

Interpretation:

The components of multi-functional enzyme cooperate to carry or channel the acyl-CoA substrate from one active site to the next in a cycle fashion needs to be described.

Concept Introduction:

Many enzymes in biochemical pathways are assembled into multifunctional enzyme complexes. The successive enzymatic reactions proceed transferring the intermediates between individual enzymes in the enzyme complex without diffusing into aqueous medium. This mode is known as channeling mechanism. In particular, enzymes in fatty acid synthesis and ß oxidation form multifunctional enzyme complexes to achieve kinetic advantages.