CONNECT ACCESS CARD FOR ANATOMY AND PHYSIOLOGY
CONNECT ACCESS CARD FOR ANATOMY AND PHYSIOLOGY
8th Edition
ISBN: 9781259880193
Author: SALADIN
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 22.3, Problem 13AYLO
Summary Introduction

To discuss:

The Haldane effect that alters the loading of CO2 with respect to the metabolic rates of individual tissues.

Introduction:

Respiration, also known as breathing is a process where oxygen (O2) is inhaled by the lungs and transported to the tissues by erythrocytes for cellular metabolism. Metabolism is a biochemical process occurring in a living cell that requires essential nutrients and oxygen to produce ATP (adenosine triphosphate) as an energy source. The amount of O2 and carbon dioxide (CO2) loading and unloading varies in different tissues with the help of the blood protein hemoglobin (Hb).  The active tissue in the body where metabolism is high consumes more amount of O2 and releases more CO2 out of the cells.

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2,3 BPG is an allosteric effector that decrease haemoglobin affinity for oxygen by stabilizing the T-state of deoxyhaemoglobin. This lead to the release of oxygen to cells and body tissues for use. H atom and CO2 are also allosteric effector and can do same. How?
. Measurements of oxygen binding by whole human blood, at 37 °C, at pH 7.4, and in the presence of 40 mm Hg of CO, and normal physiological levels of BPG (5 mmol/L of cells), give the following: Po, (mm Hg) % Saturation (=100 × Yo,) 10.6 10 19.5 30 27.4 50 37.5 70 50.4 85 77.3 96 92.3 98 (a) From these data, construct a binding curve, and estimate the per- cent oxygen saturation of blood at (1) 100 mm Hg, the approximate partial pressure of O, in the lungs, and (2) 30 mm Hg, the approxi- mate partial pressure of O, in venous blood. (b) Under these conditions, what percentage of the oxygen bound in the lungs is delivered to the tissues?
. Carbonic anhydrase of erythrocytes (M, 30,000) has one of the highest turnover numbers known. It catalyzes the reversible hydration of CO₂. H₂O + CO₂ H₂CO3 This is an important process in the transport of CO₂ from the tissues to the lungs. If 3 µg of pure carbonic anhydrase catalyzes the hydration of 0.10 g of CO₂ in 1 min at 37 °C at Vmax, what is the turnover number (kcat) of carbonic anhydrase? Keat = 3.79 ×10-¹4 Incorrect I min

Chapter 22 Solutions

CONNECT ACCESS CARD FOR ANATOMY AND PHYSIOLOGY

Ch. 22.1 - Prob. 5AYLOCh. 22.1 - Prob. 6AYLOCh. 22.1 - Prob. 7AYLOCh. 22.1 - Gross anatomy of the lungs; how the right and left...Ch. 22.1 - Prob. 9AYLOCh. 22.1 - How bronchioles differ from bronchi; two types of...Ch. 22.1 - Prob. 11AYLOCh. 22.1 - Prob. 12AYLOCh. 22.2 - Prob. 7BYGOCh. 22.2 - Prob. 8BYGOCh. 22.2 - Prob. 9BYGOCh. 22.2 - Prob. 10BYGOCh. 22.2 - Prob. 11BYGOCh. 22.2 - Suppose a healthy person has a tidal volume of 650...Ch. 22.2 - Prob. 13BYGOCh. 22.2 - Prob. 1AYLOCh. 22.2 - Prob. 2AYLOCh. 22.2 - Prob. 3AYLOCh. 22.2 - Locations and roles of the central and peripheral...Ch. 22.2 - Prob. 5AYLOCh. 22.2 - Prob. 6AYLOCh. 22.2 - Prob. 7AYLOCh. 22.2 - Prob. 8AYLOCh. 22.2 - Prob. 9AYLOCh. 22.2 - Prob. 10AYLOCh. 22.2 - Prob. 11AYLOCh. 22.2 - Prob. 12AYLOCh. 22.2 - Use of the spirometer to measure pulmonary...Ch. 22.2 - Prob. 14AYLOCh. 22.2 - Prob. 15AYLOCh. 22.2 - Prob. 16AYLOCh. 22.3 - Why is the composition of alveolar air different...Ch. 22.3 - Prob. 15BYGOCh. 22.3 - Prob. 16BYGOCh. 22.3 - Prob. 17BYGOCh. 22.3 - Prob. 18BYGOCh. 22.3 - Prob. 19BYGOCh. 22.3 - Prob. 20BYGOCh. 22.3 - Prob. 21BYGOCh. 22.3 - Prob. 22BYGOCh. 22.3 - Composition of the atmosphere and average partial...Ch. 22.3 - Prob. 2AYLOCh. 22.3 - Prob. 3AYLOCh. 22.3 - Prob. 4AYLOCh. 22.3 - Prob. 5AYLOCh. 22.3 - Prob. 6AYLOCh. 22.3 - Prob. 7AYLOCh. 22.3 - Prob. 8AYLOCh. 22.3 - Prob. 9AYLOCh. 22.3 - Prob. 10AYLOCh. 22.3 - Prob. 11AYLOCh. 22.3 - Prob. 12AYLOCh. 22.3 - Prob. 13AYLOCh. 22.3 - Prob. 14AYLOCh. 22.3 - Prob. 15AYLOCh. 22.3 - Prob. 16AYLOCh. 22.4 - Prob. 23BYGOCh. 22.4 - Prob. 24BYGOCh. 22.4 - Prob. 25BYGOCh. 22.4 - The definition of hypoxia; its four varieties and...Ch. 22.4 - Prob. 2AYLOCh. 22.4 - Prob. 3AYLOCh. 22.4 - The most common cause of lung cancer, and the...Ch. 22 - The nasal cavity is divided by the nasal septum...Ch. 22 - The intrinsic laryngeal muscles regulate speech by...Ch. 22 - The latest air passages that engage in gas...Ch. 22 - Prob. 4TYRCh. 22 - Prob. 5TYRCh. 22 - Prob. 6TYRCh. 22 - According to_______ the warming of air as it is...Ch. 22 - Prob. 8TYRCh. 22 - Prob. 9TYRCh. 22 - Prob. 10TYRCh. 22 - Prob. 11TYRCh. 22 - Within each lung, the airway forms a branching...Ch. 22 - Prob. 13TYRCh. 22 - Prob. 14TYRCh. 22 - Prob. 15TYRCh. 22 - Some inhaled air does not participate in gas...Ch. 22 - Prob. 17TYRCh. 22 - Prob. 18TYRCh. 22 - The matching of airflow to blood flow in any...Ch. 22 - Prob. 20TYRCh. 22 - Prob. 1BYMVCh. 22 - Prob. 2BYMVCh. 22 - Prob. 3BYMVCh. 22 - Prob. 4BYMVCh. 22 - eu-Ch. 22 - meterCh. 22 - Prob. 7BYMVCh. 22 - Prob. 8BYMVCh. 22 - Prob. 9BYMVCh. 22 - Prob. 10BYMVCh. 22 - Prob. 1WWTSCh. 22 - Prob. 2WWTSCh. 22 - Prob. 3WWTSCh. 22 - Prob. 4WWTSCh. 22 - Prob. 5WWTSCh. 22 - Prob. 6WWTSCh. 22 - Prob. 7WWTSCh. 22 - Prob. 8WWTSCh. 22 - Prob. 9WWTSCh. 22 - Prob. 10WWTSCh. 22 - Prob. 1TYCCh. 22 - State whether hyperventilation would raise or...Ch. 22 - Prob. 3TYCCh. 22 - Consider a man in good health with a 650 mL tidal...Ch. 22 - Prob. 5TYC
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