CONNECT IA GENERAL ORGANIC&BIO CHEMISTRY
4th Edition
ISBN: 9781260562620
Author: SMITH
Publisher: MCG
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Chapter 22.1, Problem 22.2P
-Fluorouracil is an anticancer drug that interferes with DNA synthesis because its structure resembles a DNA base that is needed for normal
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DNA Replication1) Construct the complementary strand of DNA (strand II) that would pair with the DNA strand I sequence below. Remember that nucleotides are always added in the 5 prime to 3 prime direction. The base pairing rules are:
DNA DNAadenine (A) always bonds with thymine (T) thymine (T) always bonds with adenine (A) guanine (G) always bonds with cytosine (C) cytosine (C) always bonds with guanine (G)
STRAND I: 3’ T A C T A T A G T C T G T C T C C C A C T 5’
STRAND II: 5’ 3’
2
A DNA molecule normally replicates itself millions of times, with almost no errors. What single fact about the structure is most responsible for this fidelity of replication?
Chapter 22 Solutions
CONNECT IA GENERAL ORGANIC&BIO CHEMISTRY
Ch. 22.1 - Prob. 22.1PPCh. 22.1 - Prob. 22.1PCh. 22.1 - -Fluorouracil is an anticancer drug that...Ch. 22.1 - Prob. 22.3PCh. 22.1 - Prob. 22.4PCh. 22.1 - Label each statement about the compound...Ch. 22.1 - Draw the structure of each nucleotide: (a) UMP;...Ch. 22.1 - Give the name that corresponds to each...Ch. 22.2 - Draw the structure of a dinucleotide formed by...Ch. 22.2 - Draw the structure of each polynucleotide: (a) CU;...
Ch. 22.2 - Label each statement about the polynucleotide...Ch. 22.3 - Write the complementary strand for each of the...Ch. 22.4 - What is the sequence of a newly synthesized DNA...Ch. 22.6 - For each DNA segment: [1] What is the sequence of...Ch. 22.6 - Prob. 22.9PCh. 22.7 - What amino acid is coded for by each codon? GCC...Ch. 22.7 - What codons code for each amino acid? a. glycine...Ch. 22.7 - Drive the amino acid sequence that is coded for by...Ch. 22.7 - Write a possible mRNA sequence that codes for each...Ch. 22.7 - Considering the given sequence of nucleotides in...Ch. 22.8 - Prob. 22.14PCh. 22.8 - Prob. 22.8PPCh. 22.8 - Prob. 22.9PPCh. 22.9 - Prob. 22.10PPCh. 22.9 - Prob. 22.15PCh. 22.10 - Prob. 22.16PCh. 22 - Label each statement as pertaining to DNA, RNA, or...Ch. 22 - Label each statement as pertaining to DNA, RNA, or...Ch. 22 - Prob. 19PCh. 22 - (a) Give the name of each compound shown as a...Ch. 22 - Prob. 21PCh. 22 - Prob. 22PCh. 22 - Prob. 23PCh. 22 - Prob. 24PCh. 22 - Prob. 25PCh. 22 - Draw the structure of each of the following: a...Ch. 22 - Prob. 27PCh. 22 - Prob. 28PCh. 22 - Prob. 29PCh. 22 - Prob. 30PCh. 22 - Prob. 31PCh. 22 - Draw the structures of the two possible...Ch. 22 - Prob. 33PCh. 22 - Draw the structure of each dinucleotide and...Ch. 22 - Draw the deoxyribonucleotide TGA. Label the 5 and...Ch. 22 - Draw the ribonucleotide CGU. Label the 5 and 3...Ch. 22 - Prob. 37PCh. 22 - Describe in detail the DNA double helix with...Ch. 22 - Write the sequence of the complementary strand of...Ch. 22 - Prob. 40PCh. 22 - Prob. 41PCh. 22 - Prob. 42PCh. 22 - Prob. 43PCh. 22 - Prob. 44PCh. 22 - Prob. 45PCh. 22 - Figure 22.4 snows the hydrogen-bonding...Ch. 22 - Prob. 47PCh. 22 - Prob. 48PCh. 22 - Prob. 49PCh. 22 - Prob. 50PCh. 22 - What mRNA is transcribed from each DNA sequence in...Ch. 22 - Prob. 52PCh. 22 - For each DNA segment: [1] What is the sequence of...Ch. 22 - Prob. 54PCh. 22 - For each codon, give its anticodon and the amino...Ch. 22 - For each codon, give its anticodon and the amino...Ch. 22 - Fill in the missing information in the schematic...Ch. 22 - Fill in the missing information in the schematic...Ch. 22 - Derive the amino acid sequence that is coded for...Ch. 22 - Derive the amino acid sequence that is coded for...Ch. 22 - Write a possible mRNA sequence that codes for each...Ch. 22 - Prob. 62PCh. 22 - Prob. 63PCh. 22 - Prob. 64PCh. 22 - Prob. 65PCh. 22 - Prob. 66PCh. 22 - Consider the following mRNA sequence:...Ch. 22 - Consider the following mRNA sequence: 5-ACC UUA...Ch. 22 - Consider the following sequence of DNA: 3-TTA...Ch. 22 - Consider the following sequence of DNA: 3-ATA...Ch. 22 - Prob. 71PCh. 22 - Prob. 72PCh. 22 - Prob. 73PCh. 22 - Prob. 74PCh. 22 - Prob. 75PCh. 22 - Prob. 76PCh. 22 - Prob. 77PCh. 22 - Prob. 78PCh. 22 - Prob. 79PCh. 22 - Prob. 80PCh. 22 - Prob. 81PCh. 22 - Prob. 82PCh. 22 - Fill in the base, codon, anticodon, or amino acid...Ch. 22 - Fill in the base, codon, anticodon, or amino acid...Ch. 22 - Fill in the base, codon, anticodon, or amino acid...Ch. 22 - Prob. 86PCh. 22 - Prob. 87PCh. 22 - Prob. 88PCh. 22 - Prob. 89PCh. 22 - Prob. 90PCh. 22 - Prob. 91CPCh. 22 - Give a possible nucleotide sequence in the...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Similar questions
- The DNA template strand segment 3TTCAAACCGTAC5 upon transcription and translation produces the amino acid sequence Lys-Phe-Gly-Met. What is the amino acid sequence produced if a frameshift mutation occurs in which the third A base in the original DNA sequence is removed?arrow_forwardThe base composition for one of the strands of a DNA double helix is 23% A, 31% C, 22% G, and 24% T. What is the percent base composition for the other strand of the DNA double helix?arrow_forwardDo the DNA sequences ATGC and CGTA represent the same compound? Explain.arrow_forward
- Human brain natriuretic peptide (BNP) is a small peptide of 32 amino acids used in the treatment of congestive heart failure. How many nitrogen bases are present in the DNA that codes for BNP?arrow_forwardThe base sequences in mRNA that code for certain amino acids are Glu: GAA, GAG Val: GUU, GUC, GUA, GUG Met: AUG Trp: UGG Phe: UUU, UUC Asp: GAU, GAC These sequences are complementary to the sequences in DNA. a. Give the corresponding sequences in DNA for the amino acids listed above. b. Give a DNA sequence that would code for the peptide trp-glu-phe-met. c. How many different DNA sequences can code for the tetrapeptide in part b? d. What is the peptide that is produced from the DNA sequence TACCTGAAG? e. What other DNA sequences would yield the same tripeptide as in part d?arrow_forwardWhy are the sequences of the bases in a DNA molecule important for protein synthesis?arrow_forward
- Which structure is NOT present in DNA? A B D E NH2 NH2 H3C. *NH2 H H H. Structure I is an example of OH OH HO, HỌ но HO но- -H -H- -- но -H но- -H но -H но -H H. -Он H H- -OH H- -OH H- -O- -OH H- -OH Он H HỎ он Но но OH II II IV V Structure I is an example Sugars that contain aldehyde groups that are oxidised to carboxylic acids are classified as reducing sugars. Which of the following is TRUE about structure I and II? -I and Il are non-reducing sugars -I and Il are reducing sugars - I is a non-reducing sugar, II is a reducing sugar - I is a reducing sugar, Il is a non-reducing sugar CH,OH O CH,OH но CH;OH H OH H OH CH,OH он но CH2OH O OH H H он OH H H OH но H онarrow_forwardThe "melting point" of a DNA molecule is the temperature at which the double-helical strand breaks apart. Suppose you are given two DNA samples. One sample, sample A, contains 45% G-C base pairs, while the other sample, sample B, contains 64% G-C base pairs. The total number of bases is the same in each sample. Which of the two samples, sample A or sample B, has a higher melting point? A. sample A B. sample B C. The melting point is the same for both.arrow_forwardWhy DNA does not have A 2' - OH Group?arrow_forward
- Which part of a nucleotide is involved in the bonding that holds DNA double helix together? Select one: a. The nitrogenous base of a nucleotide being repelled by the surrounding water b. The nitrogenous base of a nucleotide hydrogen bonds with the nitrogenous base of another nucleotide on the complementary strand. c. The nitrogenous base of a nucleotide hydrogen bonds with the nitrogenous base of another nucleotide on the same strand d. Interactions amongst deoxyribose sugars with phosphates on the same strand e. Interactions amongst adjacent phosphate backbonesarrow_forwardSelect the single best answer. The "melting point" of a DNA molecule is the temperature at which the double-helical strand breaks apart. Suppose you are given two DNA samples. One sample, sample A, contains 45% G-C base pairs, while the other sample, sample B, contains 64% G-C base pairs. The total number of bases is the same in each sample. Which of the two samples, sample A or sample B, has a higher melting point? sample A sample B The melting point is the same for both.arrow_forwardDefine about deoxyribonucleic acids (DNA) ?arrow_forward
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Nucleic acids - DNA and RNA structure; Author: MEDSimplified;https://www.youtube.com/watch?v=0lZRAShqft0;License: Standard YouTube License, CC-BY