ND STONY BROOK UNIVERSITY LOOSELEAF GENETICS: FROM GENES TO GENOMES
6th Edition
ISBN: 9781260406092
Author: HARTWELL, Leland, HOOD, Leroy, Goldberg, Michael
Publisher: Mcgraw-hill Education/stony Brook University
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Chapter 22, Problem 22P
Consider the triangle diagram shown in Fig. 22.17.
| a. | What feature of the genome is likely to be located between the two LD blocks that allows scientists to visualize them as separate blocks? |
| b. | Even though the figure analyzes eight different SNPs, genotyping just two of these SNPs would allow you to predict the genotype of almost everyone in the population. Explain why this limited genotyping has predictive value. |
| c. | When researchers obtain the data that enables them to build triangle diagrams, do they typically genotype common SNPs or rare SNPs? Explain. |
| d. | Considering your answer to part (c), why are human population geneticists interested in obtaining complete whole-genome sequences, as opposed to genotyping only the small subset of predictive SNPs? |
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a) Find a nitrogen base. What carbon is the base attached to?
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c)What two nitrogenous bases are held together by 3 hydrogen bonds?
You will be building a double-stranded DNA molecule, representing a short (20 base) sequence that could be found in a chromosome. It will have a 3' --> 5' strand and a 5' --> 3' strand.
Use two full 12-base-pair DNA models.
a) Upload a photo of a model once the first 6 nucleotides have been inserted to base pair with the two parent strands.
b)Upload a photo of DNA polymerase I and Ligase in "action" removing the RNA primer nucleotides and making new phosphodiester bonds.
c)Upload a photo of the final two DNA strands, after Termination, identifying the parent and daughter strands of each.
Write down the 12 base-pairs (ex A-T or G-C) contained in the two models you will us from top to bottom below
Model 1 bp:
Model 2 bp:
Chapter 22 Solutions
ND STONY BROOK UNIVERSITY LOOSELEAF GENETICS: FROM GENES TO GENOMES
Ch. 22 - Choose the best matching phrase in the right...Ch. 22 - Suppose you grew genetically identical dandelion...Ch. 22 - How can each of the following be used in...Ch. 22 - Two different groups of scientists studying a rare...Ch. 22 - Which of the following statements would be true of...Ch. 22 - Studies have indicated that for pairs of twins...Ch. 22 - Prob. 7PCh. 22 - Prob. 8PCh. 22 - Table 22.2 lists concordance values for MZ and DZ...Ch. 22 - Prob. 10P
Ch. 22 - Prob. 11PCh. 22 - Two alleles at one locus produce three distinct...Ch. 22 - In a certain plant, leaf size is determined by...Ch. 22 - Compare and contrast the use of SNP genotyping: i...Ch. 22 - Explain the similarities and differences between...Ch. 22 - In Fig. 22.14c, the fw2.2 causal gene was...Ch. 22 - Among the most prevalent pathologies that afflict...Ch. 22 - Human geneticists have found the Finnish...Ch. 22 - Canavan disease, caused by homozygosity for a...Ch. 22 - In GWAS analysis, because of the existence of LD...Ch. 22 - In Fig. 22.15: a. Why do some chromosomes in the...Ch. 22 - Consider the triangle diagram shown in Fig. 22.17....Ch. 22 - Prob. 23PCh. 22 - You conduct a Case/Control study comparing the...Ch. 22 - Prob. 25PCh. 22 - ALS amyotrophic lateral sclerosis is a rare, fatal...Ch. 22 - Through GWAS explorations, scientists have...Ch. 22 - In domesticated dogs, size has a high...Ch. 22 - Suppose a GWAS investigation found a particular LD...Ch. 22 - In 2008, Time magazine named as its invention of...
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