ND STONY BROOK UNIVERSITY LOOSELEAF GENETICS: FROM GENES TO GENOMES
ND STONY BROOK UNIVERSITY LOOSELEAF GENETICS: FROM GENES TO GENOMES
6th Edition
ISBN: 9781260406092
Author: HARTWELL, Leland, HOOD, Leroy, Goldberg, Michael
Publisher: Mcgraw-hill Education/stony Brook University
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Chapter 22, Problem 28P

In domesticated dogs, size has a high heritability, and the trait is determined by only a small number of genes. In contrast, genetic variation at more than 180 QTLs explains only a very small proportion of the high heritability for height in humans. What could explain the missing heritability in humans, and how could you test your hypothesized explanations?

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Researcher 1 studies IQ in the indigenous people of an isolated island with a population of approximately 3000 people. Researcher 2 studies IQ in North America, looking at millions of people who come from a broad range of social and economic backgrounds.  Researcher 1 concludes that 70% of the variation in IQ is genetic, whereas Researcher 2 concludes than only 40% of the variation in IQ is genetic.  What is the most likely explanation for these different estimates of the heritability of IQ?   Group of answer choices The conclusions of Researcher 2 must be flawed, because environment always has a smaller effect on IQ than genetics Widespread use of technology in North America has increased abstract reasoning ability There is less environmental variation among the people being studied by Researcher 1, so there is less opportunity for the environment to cause differences among people IQ tests measure only a subset of the abilities that constitute the concept of intelligence
In a population of locusts, the mean wing length is 47 mm, the selection gradient on wing length is β = 0.12/mm, the phenotypic variance for wing length is P = 3.6 mm2, and the heritability of wing length is h2 = 0.27. In addition, we know that the additive genetic covariance between wing and leg length is 0.60 mm2. What is the expected evolutionary change in mean leg length due to selection on both wings and legs? Repeat these calculations to predict what will happen to wing length as a result of the selection on both wings and legs. What do you predict the average wing and leg lengths will be in the next generation?
We have learned that the response to selection is equal to the selection differential times the narrow-sense heritability, and that the narrowsense heritability includes only the additive genetic variance. Why aren’t the dominance genetic variance and the gene interaction variance included? Why don’t they contribute to the genetic variation that is acted on by selection?

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ND STONY BROOK UNIVERSITY LOOSELEAF GENETICS: FROM GENES TO GENOMES

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