ND STONY BROOK UNIVERSITY LOOSELEAF GENETICS: FROM GENES TO GENOMES
ND STONY BROOK UNIVERSITY LOOSELEAF GENETICS: FROM GENES TO GENOMES
6th Edition
ISBN: 9781260406092
Author: HARTWELL, Leland, HOOD, Leroy, Goldberg, Michael
Publisher: Mcgraw-hill Education/stony Brook University
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Chapter 22, Problem 18P

Human geneticists have found the Finnish population to be very useful for studies of a variety of conditions. The population is small; Finns have extensive church records documenting lineages; and few people have migrated into Finland. The frequency of some recessive disorders is higher in the Finnish population than elsewhere in the world, and diseases such as PKU and cystic fibrosis that are common elsewhere do not occur in the Finnish population.

a. How would a population geneticist explain these variations in disease occurrence?
b. The Finnish population is also a source of information for the study of quantitative traits. The genetic basis of schizophrenia is one question that can be explored in this population. What advantage(s) and disadvantage(s) can you imagine for studying complex traits based on the Finnish population structure?
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ND STONY BROOK UNIVERSITY LOOSELEAF GENETICS: FROM GENES TO GENOMES

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