The effect on the Grignard reagent in the reaction of one equivalent of methylmagnesium iodide with ethyl acetoacetate is to be explained and the location of deuterium in the recovered ethyl acetoacetate is to be identified. Concept introduction: Grignard reagents react with ketones and aldehydes to form alcohols. These reactions are nucleophilic addition reactions. The Grignard reagent adds to the carbonyl group of aldehydes and ketones due to electronegativity difference between carbon and oxygen. A molecule that consists of a ketone group on the β- carbon atom of an ester is generally known as β- keto ester. It contains an active methylene group between two carbonyl groups in its structure. Diethyl malonate and ethyl acetoacetate are some examples of β- keto ester.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 21, Problem 34P

Interpretation Introduction

Interpretation:

The effect on the Grignard reagent in the reaction of one equivalent of methylmagnesium iodide with ethyl acetoacetate is to be explained and the location of deuterium in the recovered ethyl acetoacetate is to be identified.

Concept introduction:

Grignard reagents react with ketones and aldehydes to form alcohols. These reactions are nucleophilic addition reactions.

The Grignard reagent adds to the carbonyl group of aldehydes and ketones due to electronegativity difference between carbon and oxygen.

A molecule that consists of a ketone group on the β- carbon atom of an ester is generally known as β- keto ester. It contains an active methylene group between two carbonyl groups in its structure.

Diethyl malonate and ethyl acetoacetate are some examples of β- keto ester.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Draw the products of a reaction of the following alkyle chloride, shown below in the 3D ball and stick model with NaSCH3. Ignore inorganic byproducts. In the figure, a gray ball indicates a carbon atom a white ball indicates a hydrogen atom anda agreen ball indicated a chlorine atom

Draw the most stable cations formed in the mass spectrometer by a deavage of the following compound Draw the most stable cations formed in the mass spectrometer by a cleavage of the following compound он

Curved arrows are used to illustrate the flow of electrons. Using the provided starting anand product sytucutrs, draw the curved electron-pusing arrows for the following reaction or mechanistic steps. Be sure to account for all bond-breaking and bind-making steps

Answer 2

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 21, Problem 34P

Interpretation Introduction

Interpretation:

The effect on the Grignard reagent in the reaction of one equivalent of methylmagnesium iodide with ethyl acetoacetate is to be explained and the location of deuterium in the recovered ethyl acetoacetate is to be identified.

Concept introduction:

Grignard reagents react with ketones and aldehydes to form alcohols. These reactions are nucleophilic addition reactions.

The Grignard reagent adds to the carbonyl group of aldehydes and ketones due to electronegativity difference between carbon and oxygen.

A molecule that consists of a ketone group on the β- carbon atom of an ester is generally known as β- keto ester. It contains an active methylene group between two carbonyl groups in its structure.

Diethyl malonate and ethyl acetoacetate are some examples of β- keto ester.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 21, Problem 34P

Interpretation Introduction

Interpretation:

The effect on the Grignard reagent in the reaction of one equivalent of methylmagnesium iodide with ethyl acetoacetate is to be explained and the location of deuterium in the recovered ethyl acetoacetate is to be identified.

Concept introduction:

Grignard reagents react with ketones and aldehydes to form alcohols. These reactions are nucleophilic addition reactions.

The Grignard reagent adds to the carbonyl group of aldehydes and ketones due to electronegativity difference between carbon and oxygen.

A molecule that consists of a ketone group on the β- carbon atom of an ester is generally known as β- keto ester. It contains an active methylene group between two carbonyl groups in its structure.

Diethyl malonate and ethyl acetoacetate are some examples of β- keto ester.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 21, Problem 34P

Interpretation Introduction