The structure of product formed by the reaction of diethyl malonate with each of the reagents is to be drawn. Concept introduction: The reaction of diethyl malonate with sodium ethoxide and alkyl halide results in the formation of alkylated malonate ester. Sodium ethoxide extract α -hydrogen atom present between the two carbonyl groups and generate negative charge on carbon atom. It acts as a nucleophile and attacks the alkyl part of alkyl halide and form alkylated malonate ester. The basic hydrolysis of ester involves cleavage of − O − R bond and formation of carboxylic acid and alcohol. The decarboxylation of compound involves removal of CO 2 .

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Answer 1

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Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21, Problem 42P

Interpretation Introduction

Interpretation:

The structure of product formed by the reaction of diethyl malonate with each of the reagents is to be drawn.

Concept introduction:

The reaction of diethyl malonate with sodium ethoxide and alkyl halide results in the formation of alkylated malonate ester.

Sodium ethoxide extract α-hydrogen atom present between the two carbonyl groups and generate negative charge on carbon atom. It acts as a nucleophile and attacks the alkyl part of alkyl halide and form alkylated malonate ester.

The basic hydrolysis of ester involves cleavage of −O−R

bond and formation of carboxylic acid and alcohol. The decarboxylation of compound involves removal of CO2.

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.. Give the major organic product(s) for each of the following reactions or sequences of reactions. Show ll relevant stereochemistry [3 ONLY]. A H Br 1. NaCN 2 NaOH, H₂O, heat 3. H3O+ B. CH₂COOH 19000 1. LiAlH4 THF, heat 2 H₂O* C. CH Br 1. NaCN, acetone 2 H3O+, heat D. Br 1. Mg. ether 3. H₂O+ 2 CO₂ E. CN 1. (CH) CHMgBr, ether 2 H₂O+

Answer 2

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21, Problem 42P

Interpretation Introduction

Interpretation:

The structure of product formed by the reaction of diethyl malonate with each of the reagents is to be drawn.

Concept introduction:

The reaction of diethyl malonate with sodium ethoxide and alkyl halide results in the formation of alkylated malonate ester.

Sodium ethoxide extract α-hydrogen atom present between the two carbonyl groups and generate negative charge on carbon atom. It acts as a nucleophile and attacks the alkyl part of alkyl halide and form alkylated malonate ester.

The basic hydrolysis of ester involves cleavage of −O−R

bond and formation of carboxylic acid and alcohol. The decarboxylation of compound involves removal of CO2.

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Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21, Problem 42P

Interpretation Introduction

Interpretation:

The structure of product formed by the reaction of diethyl malonate with each of the reagents is to be drawn.

Concept introduction:

The reaction of diethyl malonate with sodium ethoxide and alkyl halide results in the formation of alkylated malonate ester.

Sodium ethoxide extract α-hydrogen atom present between the two carbonyl groups and generate negative charge on carbon atom. It acts as a nucleophile and attacks the alkyl part of alkyl halide and form alkylated malonate ester.

The basic hydrolysis of ester involves cleavage of −O−R

bond and formation of carboxylic acid and alcohol. The decarboxylation of compound involves removal of CO2.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21, Problem 42P

Interpretation Introduction